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Volume 29, Number 11—November 2023
Research Letter

Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus Mutations, Arizona, USA

LaRinda A. Holland1, Steven C. Holland1, Matthew F. Smith, Victoria R. Leonard, Vel Murugan, Lora Nordstrom, Mary Mulrow, Raquel Salgado, Michael White, and Efrem S. LimComments to Author 
Author affiliations: Arizona State University, Tempe, Arizona, USA (L.A. Holland, S.C. Holland, M.F. Smith, V.R. Leonard, V. Murugan, E.S. Lim); Valleywise Health, Phoenix, Arizona, USA (L. Nordstrom, M. Mulrow, R. Salgado, M. White)

Main Article

Figure

Genomic sequencing analysis of RSV in Arizona, USA, 2022–2023. A) Five-week moving average of PCR-confirmed RSV detections in Arizona reported to the National Respiratory and Enteric Virus Surveillance System and RSV sequence counts by genotype obtained for specimens used in this study. B) Relative abundance of RSV-A and RSV-B genotypes shown for all RSV genomes (RSV-A, n = 1,047; RSV-B, n = 941) deposited in GISAID (https://www.gisaid.org) with collection dates January 1, 2022–May 1, 2023, including genotypes obtained for specimens used in this study (RSV-A n = 100; RSV-B, n = 27). C) Reverse transcription PCR Ct values and genome coverage for RSV-A and RSV-B samples. Ct, cycle threshold; RSV, respiratory syncytial virus.

Figure. Genomic sequencing analysis of RSV in Arizona, USA, 2022–2023. A) Five-week moving average of PCR-confirmed RSV detections in Arizona reported to the National Respiratory and Enteric Virus Surveillance System and RSV sequence counts by genotype obtained for specimens used in this study. B) Relative abundance of RSV-A and RSV-B genotypes shown for all RSV genomes (RSV-A, n = 1,047; RSV-B, n = 941) deposited in GISAID (https://www.gisaid.org) with collection dates January 1, 2022–May 1, 2023, including genotypes obtained for specimens used in this study (RSV-A n = 100; RSV-B, n = 27). C) Reverse transcription PCR Ct values and genome coverage for RSV-A and RSV-B samples. Ct, cycle threshold; RSV, respiratory syncytial virus.

Main Article

1These first authors contributed equally to this article.

Page created: August 23, 2023
Page updated: October 23, 2023
Page reviewed: October 23, 2023
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