Fatal Human Neurologic Infection Caused by Pigeon Avian Paramyxovirus-1, Australia
Siobhan Hurley
1 , John Sebastian Eden
1, John Bingham, Michael Rodriguez, Matthew J. Neave, Alexandra Johnson, Annaleise R. Howard-Jones, Jen Kok, Antoinette Anazodo, Brendan McMullan, David T. Williams, James Watson, Annalisa Solinas, Ki Wook Kim
2, and William Rawlinson
2
Author affiliations: Prince of Wales Hospital, Randwick, New South Wales, Australia (S. Hurley, K.W. Kim); Westmead Institute for Medical Research Centre for Virus Research, Westmead, New South Wales, Australia (J.S. Eden); Sydney Institute for Infectious Diseases, University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia (J.S. Eden, A.R. Howard-Jones); CSIRO Australian Centre for Disease Preparedness, Geelong, Victoria, Australia (J. Bingham, M.J. Neave, D.T. Williams, J. Watson); Prince of Wales and Sydney Children’s Hospital, Randwick (M. Rodriguez, A. Solinas); Sydney Children’s Hospital, Randwick (A. Johnson, B. McMullan); Centre for Infectious Diseases and Microbiology Laboratory Services, New South Wales Health Pathology–Institute of Clinical Pathology and Medical Research, Westmead (A.R. Howard-Jones, J. Kok); Kids Cancer Centre, Sydney Children’s Hospital, Randwick (A. Anazodo); University of New South Wales Faculty of Medicine and Health, School of Clinical Medicine, Sydney (B. McMullan, K. Kim); Prince of Wales Hospital and Community Health Services, Sydney (W. Rawlinson); University of New South Wales Schools of Clinical Medicine, Biotechnology and Biomolecular Sciences, Sydney (W. Rawlinson)
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Figure 2
Figure 2. Magnetic resonance imaging of the brain of an immunocompromised child with avian paramyxovirus type 1 infection, Australia. Image, captured 16 days after hospital admission, shows predominantly left frontal and insular T2 signal hyperintensity evolving into laminar necrosis (white arrow) and hyperintensity of deep gray-matter structures (red arrows).
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