Volume 29, Number 2—February 2023
Research
Penicillin and Cefotaxime Resistance of Quinolone-Resistant Neisseria meningitidis Clonal Complex 4821, Shanghai, China, 1965–2020
Table
Frequency of identification of penicillin-nonsusceptible meningococcal isolates, Shanghai, China, 1965–2020*
Isolate source |
Total |
1965–1985 |
2005–2020 |
||
---|---|---|---|---|---|
Total |
2005–2014 |
2015–2020 |
|||
Total |
26/491 (5.3) |
1/303 (0.3) |
25/188 (13.3) |
10/143 (7.0) |
15/45 (33.3) |
IMD, n = 171 | |||||
Average | 6/17 (3.5) | 0/124 (0) | 6/47 (12.8) | 1/38 (2.6) | 5/9 (55.6) |
Age <18 y | 4/81 (4.9) | 0/46 (0) | 4/35 (11.4) | 1/29 (3.4) | 3/6 (50) |
Age >18 y |
2/90 (2.2) |
0/78 (0) |
2/12 (16.7) |
0/9 (0) |
2/3 (66.7) |
Carriage, n = 320 | |||||
Average | 20/320 (6.3) | 1/179 (0.6) | 19/141 (13.5) | 9/105 (8.6) | 10/36 (27.8) |
Age <18 y | 12/51 (23.5) | 0/8 (0) | 12/43 (27.9) | 3/22 (13.6) | 9/21 (42.9) |
Age >18 y | 8/269 (3.0) | 1/171 (0.6) | 7/98 (7.1) | 6/83 (7.2) | 1/15 (6.7) |
*Values are no./no. nonsusceptible isolates (%). IMD, invasive meningococcal disease.
1These authors contributed equally to this article.