Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 29, Number 5—May 2023
Dispatch

Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States

Sichen Liu1, Suraj Kannan1, Monica Meeks, Sandra Sanchez, Kyle W. Girone, James C. Broyhill, Roosecelis Brasil Martines, Joshua Bernick, Lori Flammia, Julia Murphy, Susan L. Hills, Kristen L. Burkhalter, Janeen J. Laven, David Gaines, and Christopher J. HoffmannComments to Author 
Author affiliations: National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA (S. Liu); Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (S. Kannan, M. Meeks, S. Sanchez, C.J. Hoffman); Virginia Department of Health, Richmond, Virginia, USA (K.W. Girone, J.C. Broyhill, J. Bernick, L. Flammia, J. Murphy, D. Gaines); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (R.B. Martines); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (S.L. Hills, K.L. Burkhalter, J.J. Laven)

Main Article

Figure 2

Viral immunostaining of samples from a fatal case of heartland virus disease acquired in the mid-Atlantic region, United States. Heartland virus antigen was detected in multiple organs. A) Mononuclear interstitial inflammatory cell of myocardium. Original magnification ×20. B) Periportal macrophages and Kupffer cells in liver. Original magnification ×20. C) Large hematopoietic cells of spleen. Original magnification ×20. D) Inflammatory interstitial cells of kidney. Original magnification ×40.

Figure 2. Viral immunostaining of samples from a fatal case of heartland virus disease acquired in the mid-Atlantic region, United States. Heartland virus antigen was detected in multiple organs. A) Mononuclear interstitial inflammatory cell of myocardium. Original magnification ×20. B) Periportal macrophages and Kupffer cells in liver. Original magnification ×20. C) Large hematopoietic cells of spleen. Original magnification ×20. D) Inflammatory interstitial cells of kidney. Original magnification ×40.

Main Article

1These first authors contributed equally to this article.

Page created: February 17, 2023
Page updated: April 19, 2023
Page reviewed: April 19, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external