Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States
Sichen Liu
1, Suraj Kannan
1, Monica Meeks, Sandra Sanchez, Kyle W. Girone, James C. Broyhill, Roosecelis Brasil Martines, Joshua Bernick, Lori Flammia, Julia Murphy, Susan L. Hills, Kristen L. Burkhalter, Janeen J. Laven, David Gaines, and Christopher J. Hoffmann
Author affiliations: National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA (S. Liu); Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (S. Kannan, M. Meeks, S. Sanchez, C.J. Hoffman); Virginia Department of Health, Richmond, Virginia, USA (K.W. Girone, J.C. Broyhill, J. Bernick, L. Flammia, J. Murphy, D. Gaines); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (R.B. Martines); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (S.L. Hills, K.L. Burkhalter, J.J. Laven)
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Figure 2
Figure 2. Viral immunostaining of samples from a fatal case of heartland virus disease acquired in the mid-Atlantic region, United States. Heartland virus antigen was detected in multiple organs. A) Mononuclear interstitial inflammatory cell of myocardium. Original magnification ×20. B) Periportal macrophages and Kupffer cells in liver. Original magnification ×20. C) Large hematopoietic cells of spleen. Original magnification ×20. D) Inflammatory interstitial cells of kidney. Original magnification ×40.
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Page created: February 17, 2023
Page updated: April 19, 2023
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