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Volume 29, Number 7—July 2023

Research Letter

Novel Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, South Korea

Sun-hak Lee, Andrew Y. Cho, Tae-hyeon Kim, Seo-jeong Ahn, Ju Ho Song, Heesu Lee, Yun-Jeong Choi, Nyamsuren Otgontogtokh, Jung-Hoon Kwon, Chang-Seon Song, and Dong-Hun LeeComments to Author 
Author affiliation: Author affiliations: Konkuk University, Seoul, South Korea (S.-h. Lee, A.Y. Cho, T.-h. Kim, S.-j. Ahn, J.H. Song, H. Lee, Y.-J. Choi, N. Otgontogtokh, C.-S. Song, D.-H. Lee); Kyungpook National University, Daegu, South Korea (J.-H. Kwon)

Main Article

Table 1

Nucleotide sequence identities between gene segments of 5 novel clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses from wild birds in South Korea and nearest homologs in the GISAID Epiflu database*

Isolates Gene Virus Accession no.† % Identity
All 5 isolates
PB2 A/goose/Hunan/SE284/2022(H5N1)/HPAI EPI2029895 99.21%
A/duck/Mongolia/826/2019 (H4N6)/LPAI EPI1777578 98.33%
HA A/turkey/Tyumen/81-96V/2021 (H5N1)/HPAI EPI1958105 99.47%
A/chicken/Tyumen/47-79V/2021 (H5N1)/HPAI EPI1957985 99.41%
NA A/goose/Hunan/SE284/2022 (H5N1)/HPAI EPI2029897 99.22%
A/duck/Bangladesh/51600/2021 (H5N1)/HPAI EPI2163444 99.15%
M
 A/ibis/Egypt/RLQP-229S/2022 (H5N1)/HPAI EPI2201158 99.80%
A/duck/Bangladesh/19D1817/2021 (H5N1)/HPAI
 EPI2062119
 99.80%
K22-730-1, K22-742, K22-856-2, K22-862-1‡
 PB1 A/Mallard/South Korea/KNU2019-20/2019 (H5N1)/LPAI EPI1902594 98.77%
A/duck/Saga/411117/2013 (H6N1)/LPAI EPI855573 98.72%
PA A/duck/Bangladesh/18D1811/2022 (H5N3)/LPAI EPI1997269 99.44%
A/duck/Bangladesh/17D1839/2022 (H5N3)/LPAI EPI1997245 99.44%
NP A/Northern Shoveler/South Korea/KNU2021-13/2021 (H11N9)/LPAI EPI2153438 99.40%
A/Mallard/South Korea/KNU2019-51/2019 (H5N3)/LPAI EPI1902887 99.33%
NS
 A/mallard/Yakutia/47/2020 (H7N7)/LPAI EPI1848197 99.52%
A/Wild duck/South Korea/KNU2020-31/2020 (H1N1)/LPAI
 EPI1931606
 99.40%
K22-920§ PB1 A/mallard/Anhui/3-617/2019 (H6N1)/LPAI EPI1743666 98.46%
A/Eurasian_Curlew/China/CZ322(7)/2019 (H3N8)/LPAI EPI1890551 98.46%
PA A/common teal/Amur region/92b/2020 (H6N2)/LPAI EPI1849993 99.26%
A/mallard/Russia Primorje/94T/2020 (H1N1)/LPAI EPI1849961 99.21%
NP A/Spot-billed duck/South Korea/KNU2020-105/2020 (H3N2)/LPAI EPI1931651 99.33%
A/Eurasian teal/South Korea/JB32-15/2019 (H10N7)/LPAI EPI1903752 98.80%
NS A/mallard/Yakutia/47/2020 (H7N7)/LPAI EPI1848197 99.28%
A/duck/Bangladesh/39397/2019 (H10N3)/LPAI EPI1778261 99.28%

*HPAI influenza viruses isolated from wild bird feces in November 2022. HA, hemagglutinin; HPAI, highly pathogenic avian influenza; LPAI, low pathogenicity avian influenza; M, matrix protein; NP, nucleoprotein; NS, nonstructural; PA, polymerase acidic; PB, polymerase basic. †Accession numbers of nearest homologs as of December 8, 2022, from GISAID (https://www.gisaid.org). ‡Genotype I. §Genotype II.

Main Article

Page created: April 29, 2023
Page updated: June 21, 2023
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