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Volume 29, Number 7—July 2023
Research

Trajectory and Demographic Correlates of Antibodies to SARS-CoV-2 Nucleocapsid in Recently Infected Blood Donors, United States

James M. Haynes, Roger Y. Dodd, Lauren A. Crowder, Edward P. Notari, and Susan L. StramerComments to Author 
Author affiliation: Author affiliations: American Red Cross, Rockville, Maryland, USA

Main Article

Figure 1

Potential nucleocapsid antibody test signal over time, showing likely sequence of S/CO values and seroconversion and seroreversion for nucleocapsid antibodies, in study of trajectory and demographic correlates of antibodies to SARS-CoV-2 nucleocapsid in recently infected blood donors, United States, June 2020‒June 2021. Each circle shows a potential value; solid circles indicate observed testing values and open circles theoretical unobserved points. The observed peak value is likely to be less that the true peak value and could occur before the true peak, in which case the slope could be affected. Blue line indicates the projected waning after the observed peak value. Ln, natural log; NC, nucleocapsid; S/CO, signal-to-cutoff value.

Figure 1. Potential nucleocapsid antibody test signal over time, showing likely sequence of S/CO values and seroconversion and seroreversion for nucleocapsid antibodies, in study of trajectory and demographic correlates of antibodies to SARS-CoV-2 nucleocapsid in recently infected blood donors, United States, June 2020‒June 2021. Each circle shows a potential value; solid circles indicate observed testing values and open circles theoretical unobserved points. The observed peak value is likely to be less that the true peak value and could occur before the true peak, in which case the slope could be affected. Blue line indicates the projected waning after the observed peak value. Ln, natural log; NC, nucleocapsid; S/CO, signal-to-cutoff value.

Main Article

Page created: April 29, 2023
Page updated: June 20, 2023
Page reviewed: June 20, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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