Volume 29, Number 7—July 2023
Research
Trajectory and Demographic Correlates of Antibodies to SARS-CoV-2 Nucleocapsid in Recently Infected Blood Donors, United States
James M. Haynes, Roger Y. Dodd, Lauren A. Crowder, Edward P. Notari, and Susan L. Stramer
Table 2
Study sample donor demographics stratified by seroreversion status during the follow-up period for study of trajectory and demographic correlates of antibodies to SARS-CoV-2 nucleocapsid in recently infected blood donors, United States, June 2020‒June 2021*
| Characteristic | Total, n = 19,323 | Nonseroreverter, n = 19,178 | Seroreverter,† n = 145 | Significance‡ |
|---|---|---|---|---|
| Sex | NS |
|||
| F | 9,965 (51.6) | 9,890 (51.6) | 75 (51.7) | |
| M |
9,358 (48.4) |
9,288 (48.4) |
70 (48.3) |
|
| Race/ethnicity | NS |
|||
| Caucasian | 18,285 (94.6) | 18,143 (94.6) | 142 (97.9) | |
| African American | 221 (1.1) | 220 (1.2) | 1 (0.7) | |
| Hispanic | 429 (2.2) | 428 (2.2) | 1 (0.7) | |
| American Indian | 46 (0.2) | 46 (0.2) | 0 | |
| >1 race | 101 (0.5) | 101 (0.5) | 0 | |
| Other | 53 (0.3) | 53 (0.3) | 0 | |
| Asian | 159 (0.8) | 159 (0.8) | 0 | |
| Missing |
29 (0.2) |
28 (0.2) |
1 (0.7) |
|
| Region | NS |
|||
| Northeast | 2,228 (11.5) | 2,215 (11.6) | 13 (8.9) | |
| Midwest | 10,274 (53.2) | 10,199 (53.2) | 75 (51.7) | |
| South | 3,998 (20.7) | 3,965 (20.7) | 33 (22.8) | |
| West | 2,818 (14.6) | 2,794 (14.6) | 24 (16.6) | |
| Missing |
5 (0.03) |
5 (0.03) |
0 |
|
| Mean age, y (SD) |
52.3 (13.9) |
52.3 (13.9) |
49.6 (13.6) |
p = 0.01 |
| BMI, kg/m2 (SD) | 28.8 (5.7) | 28.8 (5.7) | 27.4 (5.4) | p<0.01 |
*Values are no. (%) unless otherwise indicated. BMI, body mass index; NS, not significant; S/CO, signal-to-cutoff value. †Donor with any donation after the peak S/CO with loss of nucleocapsid reactivity (S/CO <1.0). ‡G-test of independence was used for categorical significance tests comparing demographics of seroreverting and nonseroreverting donors.
Page created: April 29, 2023
Page updated: June 20, 2023
Page reviewed: June 20, 2023
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