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Volume 29, Number 9—September 2023
Dispatch

Population Analysis of Escherichia coli Sequence Type 361 and Reduced Cefiderocol Susceptibility, France

Agnès B. JoussetComments to Author , Laura Bouabdallah, Aurélien Birer, Isabelle Rosinski-Chupin, Jean-François Mariet, Saoussen Oueslati, Cécile Emeraud, Delphine Girlich, Philippe Glaser, Thierry Naas, Rémy A. Bonnin, and Laurent Dortet
Author affiliations: Bicêtre Hospital Bacteriology Hygiene, Le Kremlin-Bicetre, France (A.B. Jousset, J.-F. Mariet, C. Emeraud, T. Naas, R.A. Bonnin, L. Dortet); Institut National de la Santé et de la Recherche Médicale, Paris, France (A.B. Jousset, L. Bouabdallah, S. Oueslati, C. Emeraud, D. Girlich, T. Naas, R.A. Bonnin, L. Dortet); Centre National de Référence de la Résistance aux Antibiotiques, Le Kremlin-Bicetre (A.B. Jousset, J.-F. Mariet, C. Emeraud, T. Naas, R.A. Bonnin, L. Dortet); Centre National de Référence de la Résistance aux Antibiotiques, Clermont-Ferrand, France (A. Birer); Institut Pasteur, Paris (I. Rosinski-Chupin, P. Glaser); Universite Paris-Sud, Paris (T. Naas)

Main Article

Figure 1

Evolution of NDM-producing and non–NDM-producing CPE observed in a population analysis of Escherichia coli ST361 and reduced cefiderocol susceptibility, France. A) Evolution of non-CPE CRE, non-NDM CRE, and non–NDM-producing Enterobacterales sent to the French National Reference Center for Antimicrobial Resistance during 2014–2022. B) Distribution of cefiderocol MICs in all (n = 856) CRE isolates collected during the study, July 1, 2021–June 30, 2022. C) Distribution of cefiderocol MICs in all (n = 80) E. coli ST361 isolates from the French National Reference Center for Antimicrobial Resistance collection, 2015–2022. CPE, carbapenemase-producing Enterobacterales; CRE, carbapenem-resistant Enterobacterales; NDM, New Delhi metallo-β-lactamase; non-CPE, non–carbapenemase producing; non-NDM CPE, non–NDM carbapenemase-producing Enterobacterales; ST, sequence type.

Figure 1. Evolution of NDM-producing and non–NDM-producing CPE observed in a population analysis of Escherichia coli ST361 and reduced cefiderocol susceptibility, France. A) Evolution of non-CPE CRE, non-NDM CRE, and non–NDM-producing Enterobacterales sent to the French National Reference Center for Antimicrobial Resistance during 2014–2022. B) Distribution of cefiderocol MICs in all (n = 856) CRE isolates collected during the study, July 1, 2021–June 30, 2022. C) Distribution of cefiderocol MICs in all (n = 80) E. coli ST361 isolates from the French National Reference Center for Antimicrobial Resistance collection, 2015–2022. CPE, carbapenemase-producing Enterobacterales; CRE, carbapenem-resistant Enterobacterales; NDM, New Delhi metallo-β-lactamase; non-CPE, non–carbapenemase producing; non-NDM CPE, non–NDM carbapenemase-producing Enterobacterales; ST, sequence type.

Main Article

Page created: July 14, 2023
Page updated: August 20, 2023
Page reviewed: August 20, 2023
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