Volume 30, Number 11—November 2024
Dispatch
Genomic Epidemiology of Human Respiratory Syncytial Virus, Minnesota, USA, July 2023–February 2024
Daniel Evans
, Henry Kunerth, Erica Mumm, Sarah Namugenyi, Matthew Plumb, Sarah Bistodeau, Scott A. Cunningham, Bryan Schmitt, Karen Martin, Katherine Como-Sabetti, Ruth Lynfield, and Xiong Wang
, Henry Kunerth, Erica Mumm, Sarah Namugenyi, Matthew Plumb, Sarah Bistodeau, Scott A. Cunningham, Bryan Schmitt, Karen Martin, Katherine Como-Sabetti, Ruth Lynfield, and Xiong Wang
Table 1
Whole-genome sequencing results for RSV-A and RSV-B specimens collected from patients in Minnesota, USA, July 2023–February 2024*
| Whole-genome lineage | No. (% of subgroup) | Cases in RSV-NET (% of WGS lineage) | Twin Cities metro (% of WGS lineage) | Mean pairwise phylogenetic distance | Earliest specimen collection, mo | Estimated time to most recent common ancestor (95% CI) |
|---|---|---|---|---|---|---|
| A.D.1 |
31 (10.8) |
2 (6.5) |
26 (83.9) |
0.00555 |
2023 Sep |
Jun 2017 (Jan 1996–Jan 2021) |
| A.D.3 |
53 (18.5) |
5 (9.4) |
40 (75.5) |
0.00718 |
2023 Aug |
Aug 2017 (Jun 1996–Jan 2021) |
| A.D.3.1 |
1 (0.3) |
0 |
1 (100) |
NA |
2024 Jan |
NA |
| A.D.5 |
109 (38.0) |
25 (22.9) |
103 (94.5) |
0.00076 |
2023 Aug |
Aug 2018 (Mar 2002–Nov 2021) |
| A.D.5.1 |
1 (0.3) |
0 |
1 (100) |
NA |
2023 Dec |
NA |
| A.D.5.2 |
91 (31.7) |
32 (35.1) |
74 (81.3) |
0.00252 |
2023 Oct |
Apr 2021 (May 2015–Oct 2022) |
| A.D.5.3 |
1 (0.3) |
0 |
NA (unknown) |
NA |
2023 Sep |
NA |
| B.D.4.1.1 |
12 (4.2) |
4 (33.3) |
12 (100) |
0.00513 |
2023 Oct |
Mar 2015 (Jun 1976–May 2019) |
| B.D.E.1 |
274 (95.1) |
49 (17.9) |
189 (69) |
0.00384 |
2023 Jul |
Oct 2019 (Nov 2000–Jul 2021) |
| B.D.E.2 | 2 (0.7) | 0 | 2 (100) | NA | 2023 Jul | NA |
*Counts and percentages exclude cases with out-of-state or of unknown residence. Pairwise phylogenetic distances and estimated times of most recent common ancestors were calculated using Minnesota HRSV genomes only for lineages with >3 genomes. NA, not applicable; RSV, respiratory syncytial virus; RSV-NET, Respiratory Syncytial Virus Hospitalization Surveillance Network; Twin Cities Metro, Minneapolis-St Paul metropolitan area; WGS, whole-genome sequencing.
Page created: September 24, 2024
Page updated: October 22, 2024
Page reviewed: October 22, 2024
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