Volume 30, Number 11—November 2024
Dispatch
Genomic Epidemiology of Human Respiratory Syncytial Virus, Minnesota, USA, July 2023–February 2024
Daniel Evans
, Henry Kunerth, Erica Mumm, Sarah Namugenyi, Matthew Plumb, Sarah Bistodeau, Scott A. Cunningham, Bryan Schmitt, Karen Martin, Katherine Como-Sabetti, Ruth Lynfield, and Xiong Wang
, Henry Kunerth, Erica Mumm, Sarah Namugenyi, Matthew Plumb, Sarah Bistodeau, Scott A. Cunningham, Bryan Schmitt, Karen Martin, Katherine Como-Sabetti, Ruth Lynfield, and Xiong Wang
Table 1
Whole-genome sequencing results for RSV-A and RSV-B specimens collected from patients in Minnesota, USA, July 2023–February 2024*
| Whole-genome lineage | No. (% of subgroup) | Cases in RSV-NET (% of WGS lineage) | Twin Cities metro (% of WGS lineage) | Mean pairwise phylogenetic distance | Earliest specimen collection, mo | Estimated time to most recent common ancestor (95% CI) |
|---|---|---|---|---|---|---|
| A.D.1 |
31 (10.8) |
2 (6.5) |
26 (83.9) |
0.00555 |
2023 Sep |
Jun 2017 (Jan 1996–Jan 2021) |
| A.D.3 |
53 (18.5) |
5 (9.4) |
40 (75.5) |
0.00718 |
2023 Aug |
Aug 2017 (Jun 1996–Jan 2021) |
| A.D.3.1 |
1 (0.3) |
0 |
1 (100) |
NA |
2024 Jan |
NA |
| A.D.5 |
109 (38.0) |
25 (22.9) |
103 (94.5) |
0.00076 |
2023 Aug |
Aug 2018 (Mar 2002–Nov 2021) |
| A.D.5.1 |
1 (0.3) |
0 |
1 (100) |
NA |
2023 Dec |
NA |
| A.D.5.2 |
91 (31.7) |
32 (35.1) |
74 (81.3) |
0.00252 |
2023 Oct |
Apr 2021 (May 2015–Oct 2022) |
| A.D.5.3 |
1 (0.3) |
0 |
NA (unknown) |
NA |
2023 Sep |
NA |
| B.D.4.1.1 |
12 (4.2) |
4 (33.3) |
12 (100) |
0.00513 |
2023 Oct |
Mar 2015 (Jun 1976–May 2019) |
| B.D.E.1 |
274 (95.1) |
49 (17.9) |
189 (69) |
0.00384 |
2023 Jul |
Oct 2019 (Nov 2000–Jul 2021) |
| B.D.E.2 | 2 (0.7) | 0 | 2 (100) | NA | 2023 Jul | NA |
*Counts and percentages exclude cases with out-of-state or of unknown residence. Pairwise phylogenetic distances and estimated times of most recent common ancestors were calculated using Minnesota HRSV genomes only for lineages with >3 genomes. NA, not applicable; RSV, respiratory syncytial virus; RSV-NET, Respiratory Syncytial Virus Hospitalization Surveillance Network; Twin Cities Metro, Minneapolis-St Paul metropolitan area; WGS, whole-genome sequencing.
Page created: September 24, 2024
Page updated: October 22, 2024
Page reviewed: October 22, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.