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Volume 30, Number 12—December 2024
CME ACTIVITY - Research

Ophthalmic Sequelae of Ebola Virus Disease in Survivors, Sierra Leone

Charlene H. Choo, Laura Ward, Ian Crozier, Tolulope Fashina, Daisy Yan, Brent R. Hayek, Caleb Hartley, Matthew Vandy, John G. Mattia, Lloyd Harrison-Williams, Jalikatu Mustapha, Carolyn Drews-Botsch, Steven Yeh1, and Jessica Shantha1Comments to Author 
Author affiliation: University of Nebraska Medical Center, Omaha, Nebraska, USA (C.H. Choo, T. Fashina, C. Hartley, S. Yeh); Emory University, Atlanta, Georgia, USA (L. Ward, S. Yeh, J. Shantha); Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA (I. Crozier); University of California, San Francisco, California, USA (D. Yan, J. Shantha); North Georgia Eye Clinic, Gainesville, Georgia, USA (B.R. Hayek); Ministry of Health and Sanitation, Freetown, Sierra Leone (M. Vandy, J.G. Mattia, L. Harrison-Williams, J. Mustapha); George Mason University, Fairfax, Virginia, USA (C. Drews-Botsch)

Main Article

Table 5

Ophthalmic examination findings associated with uveitis status in eyes of survivors in study of ophthalmic sequelae after Ebola virus disease, Sierra Leone*

Ophthalmic exam finding No. (%) eyes
 OR (95% CI) p value
Total, N = 1,042 Uveitis, n = 86 No uveitis, n = 956
Bullous keratopathy 2 (0.2) 1 (50.0) 1 (50.0) 11.13 (8.67–14.51) <0.001
Cataract 117 (11.2) 14 (12.0) 103 (88.0) 1.94 (0.96–3.89) 0.065
Corneal scar 28 (2.7) 5 (17.9) 23 (82.1) 1.94 (0.59–6.37) 0.276
Chorioretinal scar 68 (6.5) 17 (25.0) 51 (75.0) 3.74 (1.84–7.62) 0.012
Optic neuropathy 7 (0.7) 6 (85.6) 1 (14.3) 1.53 (0.07–34.47) 0.790
Posterior synechiae 7 (0.7) 3 (42.9) 4 (57.1) 11.58 (2.23–55.98) 0.002
Retinal detachment 7 (0.7) 3 (42.9) 4 (57.1) 5.64 (1.46–21.67) 0.012
Vitreous opacity
 21 (2.0)
 8 (38.1)
 13 (61.9)
 5.41 (2.04–14.45)
 0.022
Visual acuity
20/40 or better 783 (75.1) 54 (6.9) 729 (93.1) 2.25 (1.32–3.83) 0.004
20/50 or worse 259 (24.9) 32 (12.4) 227 (87.6) NA NA

*NA, not applicable; OR, odds ratio.

Main Article

1These authors were co–principal investigators.

Page created: November 04, 2024
Page updated: November 22, 2024
Page reviewed: November 22, 2024
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