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Volume 30, Number 12—December 2024
CME ACTIVITY - Research

Ophthalmic Sequelae of Ebola Virus Disease in Survivors, Sierra Leone

Charlene H. Choo, Laura Ward, Ian Crozier, Tolulope Fashina, Daisy Yan, Brent R. Hayek, Caleb Hartley, Matthew Vandy, John G. Mattia, Lloyd Harrison-Williams, Jalikatu Mustapha, Carolyn Drews-Botsch, Steven Yeh1, and Jessica Shantha1Comments to Author 
Author affiliation: University of Nebraska Medical Center, Omaha, Nebraska, USA (C.H. Choo, T. Fashina, C. Hartley, S. Yeh); Emory University, Atlanta, Georgia, USA (L. Ward, S. Yeh, J. Shantha); Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA (I. Crozier); University of California, San Francisco, California, USA (D. Yan, J. Shantha); North Georgia Eye Clinic, Gainesville, Georgia, USA (B.R. Hayek); Ministry of Health and Sanitation, Freetown, Sierra Leone (M. Vandy, J.G. Mattia, L. Harrison-Williams, J. Mustapha); George Mason University, Fairfax, Virginia, USA (C. Drews-Botsch)

Main Article

Table 6

Multivariable model of ophthalmic findings and vision impairment in eyes of survivors in study of ophthalmic sequelae after Ebola virus disease, Sierra Leone*

Ophthalmic finding No. (%) eyes
 OR (95% CI) p value
Vision impairment, n = 259 No vision impairment, n = 783
Cataract 71 (27.4) 46 (5.9) 7.68 (4.32–13.64) <0.001
Uveitis 32 (12.4) 54 (7.0) 2.08 (1.23–3.52) 0.0065
Corneal scar 12 (4.6) 16 (2.0) 4.23 (1.80–9.95) 0.0010
Optic neuropathy 5 (1.9) 2 (0.3) 6.32 (1.15–34.69) 0.0335

*Vision impairment was defined as visual acuity worse than 20/50 Snellen. OR, odds ratio.

Main Article

1These authors were co–principal investigators.

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