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Volume 30, Number 2—February 2024
Synopsis

Parechovirus A Circulation and Testing Capacities in Europe, 2015–2021

Laura BubbaComments to Author , Eeva K. Broberg, Thea K. Fischer, Peter Simmonds, Heli Harvala, and European Non-polio Enterovirus Network working group
Author affiliations: European Non-Polio Enterovirus Network, Geneva, Switzerland (L. Bubba); European Centre for Disease Prevention and Control, Solna, Sweden (E.K. Broberg); University Hospital of Nordsjaelland Department of Clinical Research, Hilleroed, Denmark (T.K. Fischer); University of Copenhagen Department of Public Health, Copenhagen, Denmark (T.K. Fischer); University of Oxford Nuffield Department of Medicine, Oxford, UK (P. Simmonds); National Health Service Blood and Transplant, London, UK (H. Harvala); University College London Division of Infection and Immunity, London (H. Harvala)

Main Article

Table

Information about institutions included in study of parechovirus testing, surveillance, and genotyping capacities, Europe*

Country (region)† Institution type PeV-A testing capacity Timeframe of data National surveillance Testing trigger Genotyping capacity Routine genotyping
Austria
Hospital virology or microbiology laboratory
Yes
2015–2021
No
Upon clinical request; all CSF from children <12 mo sent to institute tested for PeV-A
Yes
No
Denmark
National PH institute
Yes
2015–2021
Yes
Surveillance system: positive samples from clinical microbiology laboratories after clinical request forwarded to SSI for sequencing
Yes
Yes
Finland
Hospital virology/ microbiology laboratory
Yes
2015–2021
Yes‡
Upon clinical request
Yes
No
Ireland
Diagnostic and virus reference laboratory
Yes
2015–2021
No
Passive surveillance system triggered by clinical request. PeV-A testing on all CSF from CNS virology screen from children <3 y
No
NA
Italy (Lombardy)
Regional PH institute and academic institution
Yes
2015–2021
No§
ILI and AFP surveillance, clinical requests
Yes
Yes
Italy (Lombardy)
Hospital virology/ microbiology laboratory and academic institution
Yes
2015–2021
No
Hospital request for PeV-A testing in patients with clinical manifestations of meningo-encephalitis, encephalitis, or sepsis
Yes
Yes
Italy (Lombardy)
Hospital microbiology
Yes
2015–2021
No
Upon clinical request
No¶
NA
Slovenia
Academia
Yes
2015–2021
No
Upon clinical request
Yes
No
Spain
National PH institute
Yes
2015–2021
Yes‡
No specific criteria; Nacional Centre for Microbiology’s Enterovirus and Parechovirus Reference Lab receives 500–700/y EV- and PeV-A-positive samples voluntarily submitted for genotyping and 20–30/y samples for EV/PeV testing
Yes
Yes
UK (England)
National PH institute
Yes
2015–2021
Yes‡
Samples from non-polio EV passive surveillance system. Voluntarily submitted samples PeV-A-positive samples for confirmation and genotyping. (voluntary because PeV-A is not a notifiable pathogen)
Yes
No
Netherlands
Hospital virology/ microbiology laboratory and academic institution
Yes
2015–2021
Yes‡
Samples from the non-polio EV passive surveillance system
Yes
Yes
Norway
National PH institute
Yes
2015–2017
No
Upon clinical request
No
No#
UK (Scotland)
National PH institute
Yes
2015–2017
No
Upon clinical request
Yes
No#
Luxembourg
National PH institute
Yes
2015–2021
No
CSF from clinical requests
No
NA
Slovenia
National PH institute
Yes
2015–2021
No§
ILI surveillance system
No
NA
Poland
National PH institute
Yes
2015–2021
No
Upon clinical request
Yes
No
Bulgaria
National PH institute
Not yet performed
No data reported
Not yet performed
Not yet implemented
NA
NA
Czechia
National PH institute
No
No data reported
No
None
NA
NA
Estonia
National PH institute
No
No data reported
No
None
NA
NA
Hungary
National PH institute
No
No data reported
Unknown
None
NA
NA
Slovak Republic National PH institute No No data reported No None NA NA

*ACP, acute flaccid paralysis; CNS, central nervous system; CSF, cerebrospinal fluid; EV, enteroviruses; PeV-A, parechovirus type A; ILI, influenza-like illness; PH, public health; SSI, Statens Serum Institut. †Countries of origin of the participating laboratories. ‡Implemented in the passive non-polio enterovirus surveillance. §All respiratory samples collected for the influenza-like illness surveillance were screened for parechoviruses. ¶Parechovirus-positive samples were sent to the regional reference laboratory for sequencing. #All samples included in the acute flaccid paralysis (AFP) surveillance are also screened for parechovirus.

Main Article

Page created: December 13, 2023
Page updated: January 25, 2024
Page reviewed: January 25, 2024
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