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Volume 30, Number 4—April 2024
Research

Divergent Pathogenesis and Transmission of Highly Pathogenic Avian Influenza A(H5N1) in Swine

Bailey ArrudaComments to Author , Amy L. Vincent Baker, Alexandra Buckley, Tavis K. Anderson, Mia Torchetti, Nichole Hines Bergeson, Mary Lea Killian, and Kristina Lantz
Author affiliations: Agriculture Research Service, Ames, Iowa, USA (B. Arruda, A.L. Vincent Baker, A. Buckley, T.K. Andersen); Animal and Plant Health Inspection Service, Ames (M. Torchetti, N. Hines Bergeson, M.L. Killian, K. Lantz)

Main Article

Figure 2

Violin plots showing Ct values for bronchoalveolar lavage fluid from pigs, by virus strain and dpi, in study of divergent pathogenesis and transmission of highly pathogenic avian influenza A(H5N1) in swine. Values were determined by quantitative reverse transcription PCR (ThermoFisher Scientific, https://www.thermofisher.com). All strains replicated in the lung of pigs. No statistical difference was detected between strains by dpi. Solid lines within plots indicate medians, dashed lines indicate quartiles, and symbols indicate individual pig values. dpi, days postinoculation; Eagle 3 dpi, A/bald eagle/FL/22 necropsied on 3 dpi; Eagle 5 dpi, A/bald eagle/FL/22 necropsied at 5 dpi; Fox 3 dpi, A/redfox/MI/22 necropsied at 3 dpi; Fox 5 dpi, A/redfox/MI/22 necropsied at 5 dpi; Racoon 3 dpi, A/raccoon/WA/22 necropsied at 3 dpi; Racoon 5 dpi, A/raccoon/WA/22 necropsied at 5 dpi; Turkey 3 dpi, A/turkey/MN/22 necropsied at 3 dpi; Turkey 5 dpi, A/turkey/MN/22 necropsied at 5 dpi.

Figure 2. Violin plots showing Ct values for bronchoalveolar lavage fluid from pigs, by virus strain and dpi, in study of divergent pathogenesis and transmission of highly pathogenic avian influenza A(H5N1) in swine. Values were determined by quantitative reverse transcription PCR (ThermoFisher Scientific, https://www.thermofisher.com). All strains replicated in the lung of pigs. No statistical difference was detected between strains by dpi. Solid lines within plots indicate medians, dashed lines indicate quartiles, and symbols indicate individual pig values. dpi, days postinoculation; Eagle 3 dpi, A/bald eagle/FL/22 necropsied on 3 dpi; Eagle 5 dpi, A/bald eagle/FL/22 necropsied at 5 dpi; Fox 3 dpi, A/redfox/MI/22 necropsied at 3 dpi; Fox 5 dpi, A/redfox/MI/22 necropsied at 5 dpi; Racoon 3 dpi, A/raccoon/WA/22 necropsied at 3 dpi; Racoon 5 dpi, A/raccoon/WA/22 necropsied at 5 dpi; Turkey 3 dpi, A/turkey/MN/22 necropsied at 3 dpi; Turkey 5 dpi, A/turkey/MN/22 necropsied at 5 dpi.

Main Article

Page created: March 07, 2024
Page updated: March 20, 2024
Page reviewed: March 20, 2024
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