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Volume 30, Number 4—April 2024
Research

Divergent Pathogenesis and Transmission of Highly Pathogenic Avian Influenza A(H5N1) in Swine

Bailey ArrudaComments to Author , Amy L. Vincent Baker, Alexandra Buckley, Tavis K. Anderson, Mia Torchetti, Nichole Hines Bergeson, Mary Lea Killian, and Kristina Lantz
Author affiliations: Agriculture Research Service, Ames, Iowa, USA (B. Arruda, A.L. Vincent Baker, A. Buckley, T.K. Andersen); Animal and Plant Health Inspection Service, Ames (M. Torchetti, N. Hines Bergeson, M.L. Killian, K. Lantz)

Main Article

Figure 4

Violin plots of weighted macroscopic lung scores, by virus strain and dpi, of swine infected with highly pathogenic avian influenza A(H5N1) virus belonging to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic clade. All strains caused macroscopic lesions consistent with influenza A virus infection in >1 pig. Solid lines within plots indicate medians, dashed lines indicate quartiles, and symbols indicate individual pig values. No statistically significant differences were detected between strains by dpiI. dpi, days postinoculation; eagle 3 dpi, A/bald eagle/FL/22 necropsied at 3 dpi; eagle 5 dpi, A/bald eagle/FL/22 necropsied at 5 dpi; fox 3 dpi, A/redfox/MI/22 necropsied at 3 dpi; fox 5 dpi, A/redfox/MI/22 necropsied at 5 dpi; raccoon 3 dpi, A/raccoon/WA/22 necropsied at 3 dpi; raccoon 5 dpi, A/raccoon/WA/22 necropsied at 5 dpi; turkey 3 dpi, A/turkey/MN/22 necropsied at 3 dpi; turkey 5 dpi, A/turkey/MN/22 necropsied at 5 dpi.

Figure 4. Violin plots of weighted macroscopic lung scores, by virus strain and dpi, of swine infected with highly pathogenic avian influenza A(H5N1) virus belonging to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic clade. All strains caused macroscopic lesions consistent with influenza A virus infection in >1 pig. Solid lines within plots indicate medians, dashed lines indicate quartiles, and symbols indicate individual pig values. No statistically significant differences were detected between strains by dpiI. dpi, days postinoculation; eagle 3 dpi, A/bald eagle/FL/22 necropsied at 3 dpi; eagle 5 dpi, A/bald eagle/FL/22 necropsied at 5 dpi; fox 3 dpi, A/redfox/MI/22 necropsied at 3 dpi; fox 5 dpi, A/redfox/MI/22 necropsied at 5 dpi; raccoon 3 dpi, A/raccoon/WA/22 necropsied at 3 dpi; raccoon 5 dpi, A/raccoon/WA/22 necropsied at 5 dpi; turkey 3 dpi, A/turkey/MN/22 necropsied at 3 dpi; turkey 5 dpi, A/turkey/MN/22 necropsied at 5 dpi.

Main Article

Page created: March 07, 2024
Page updated: March 20, 2024
Page reviewed: March 20, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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