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Volume 30, Number 4—April 2024
Research

Clostridium butyricum Bacteremia Associated with Probiotic Use, Japan

Ryuichi Minoda SadaComments to Author , Hiroo Matsuo, Daisuke Motooka, Satoshi Kutsuna, Shigeto Hamaguchi, Go Yamamoto, and Akiko Ueda
Author affiliations: Osaka University Graduate School of Medicine, Osaka, Japan (R.M. Sada, H. Matsuo, S. Kutsuna, S. Hamaguchi, G. Yamamoto); Osaka University Research Institute for Microbial Diseases, Osaka (D. Motooka); Osaka University Hospital, Suita, Osaka (A. Ueda)

Main Article

Table 3

Results of whole-genome sequencing of Clostridium butyricum obtained from blood culture from 5 patients who tested positive for Clostridium butyricum in a single-institute, retrospective study, Osaka University Hospital, Japan

Category
 Patient strains
Patient no.
 1
 2
 3
 4
 5
Strain no. 114–4 129–32 180–11 181–16 216–41
Average nucleotide identity* against CBM 588 strains 99.986 99.947 99.949 99.943 99.946
All variants† 50 40 63 65 81
Variants not on rRNA region‡ 19 1 2 1 0

*Calculated using FastANI (31). †Number of all variants in coding genes, which were called and annotated by GATK HaplotypeCaller (32) and snpEff (33) with annotation information from DFAST (34). ‡Number of variants after excluding variants on rRNA region.

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Page updated: March 20, 2024
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