Volume 30, Number 5—May 2024
Synopsis
Congenital Syphilis Prevention Challenges, Pacific Coast of Colombia, 2018–2022
Table 1
Bivariate analysis of factors associated with having newborns with congenital syphilis in mothers who entered in a prenatal care program of a public hospital in Buenaventura, Colombia, 2018–2022*
| Characteristic | Newborn with congenital syphilis |
Newborn without congenital syphilis |
Crude OR (95% CI) | p value | ||
|---|---|---|---|---|---|---|
| Age group, y | ||||||
| <18 | ||||||
| Yes | 19 (19.8) | 592 (18.0) | 1.12 (0.63–1.89) | 0.659 | ||
| No | 77 (80.2) | 2,690 (82.0) | Referent | |||
| 19–34 | ||||||
| Yes | 72 (75.0) | 2,403 (73.2) | 1.09 (0.68–1.83) | 0.697 | ||
| No | 24 (25.0) | 879 (26.8) | Referent | |||
| >35 | ||||||
| Yes | 5 (5.2) | 287 (8.7) | 0.57 (0.18–1.40) | 0.224† | ||
| No |
91 (94.8) |
2,995 (91.3) |
Referent |
|||
| Educational level | ||||||
| Basic or lower‡ | 92 (95.8) | 3,115 (94.9) | 1.23 (0.45–4.67) | 0.684 | ||
| Postsecondary |
4 (4.2) |
167 (5.1) |
Referent |
|||
| Socioeconomic stratum§ | ||||||
| 1 (low-low) | 94 (97.9) | 3,075 (93.7) | 3.16 (0.84–26.68) | 0.090† | ||
| 2 (low) |
2 (2.1) |
207 (6.3) |
Referent |
|||
| Residential area | ||||||
| Rural | 1 (1.0) | 148 (4.5) | 0.22 (0.01–1.29) | 0.102† | ||
| Urban |
95 (99.0) |
3,134 (95.5) |
Referent |
|||
| Ethnicity | ||||||
| Afro-Colombian | 92 (95.8) | 3,234 (98.5) | 0.34 (0.12–1.33) | 0.033† | ||
| Other |
4 (4.2) |
48 (1.5) |
Referent |
|||
| Occupation | ||||||
| Head of household¶ | 77 (80.2) | 2,580 (78.6) | 1.1 (0.65–1.94) | 0.706 | ||
| Other |
19 (19.8) |
702 (21.4) |
Referent |
|||
| Marital status | ||||||
| Single | 24 (25.0) | 621 (18.9) | 1.42 (0.85–2.31) | 0.135† | ||
| With partner# |
72 (75.0) |
2,661 (81.1) |
Referent |
|||
| History of >3 pregnancies | ||||||
| Yes | 33 (34.4) | 1,024 (31.2) | 1.15 (0.73–1.80) | 0.508 | ||
| No |
63 (65.6) |
2,258 (68.8) |
Referent |
|||
| History of spontaneous abortions | ||||||
| Yes | 23 (24.0) | 655 (20.0) | 1.26 (0.75–2.1) | 0.334 | ||
| No |
73 (76.0) |
2,627 (80.0) |
Referent |
|||
| History of stillbirths | ||||||
| Yes | 3 (3.1) | 89 (2.7) | 1.16 (0.23–3.60) | 0.806 | ||
| No |
93 (96.9) |
3,193 (97.3) |
Referent |
|||
| Trimester of access to PCP | ||||||
| Second or third | 50 (52.1) | 1,526 (46.5) | 1.25 (0.81–1.92) | 0.279 | ||
| First |
46 (47.9) |
1,756 (53.5) |
Referent |
|||
| >1 syphilis screening test | ||||||
| No | 51 (53.1) | 1,188 (36.2) | 1.99 (1.30–3.07) | <0.001† | ||
| Yes | 45 (46.9) |
2,094 (63.8) |
Referent | |||
*Values are no. (%) except as indicated. PCP, prenatal care program. †Indicates variables with a p value of <0.25 included in the logistic regression. ‡Basic or lower: completed secondary school or lower; post-secondary: technical, technologist, university, or higher. §Socioeconomic stratum scale in Colombia: 1 to 6, with 1 being the lowest level. ¶Person, whether single or married, who bears the ongoing responsibility for providing financial or social support to their minor newborns or other dependents. #De facto marriage or married.
1These first authors contributed equally to this article.