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Volume 30, Number 5—May 2024
Synopsis

Congenital Syphilis Prevention Challenges, Pacific Coast of Colombia, 2018–2022

Jose F. Fuertes-Bucheli1, Diana P. Buenaventura-Alegría1, Adriana M. Rivas-Mina, and Robinson Pacheco-LópezComments to Author 
Author affiliations: Universidad Icesi, Cali, Colombia (J.F. Fuertes-Bucheli, R. Pacheco-López); Centro Internacional de Entrenamiento e Investigaciones Médicas–CIDEIM, Cali (J.F. Fuertes-Bucheli); Hospital Distrital Luis Ablanque de la Plata, Buenaventura, Colombia (D.P. Buenaventura-Alegría); Universidad Libre, Cali (D.P. Buenaventura-Alegría, A.M. Rivas-Mina)

Main Article

Table 3

Analysis of maternal factors associated with having a newborn with congenital syphilis in pregnant women with syphilis at a public hospital, Buenaventura, Colombia, 2018–2022*

Characteristic Newborn with congenital syphilis
 Newborn without congenital syphilis
 RR (95% CI) p value
Age group, y
<18
Yes 9 (22.0) 35 (18.1) 1.21 (0.62–2.35) 0.570
No 32 (78.0) 158 (81.9) Referent
19–34
Yes 30 (73.2) 146 (75.6) 0.89 (0.48–1.67) 0.738
No 11 (26.8) 47 (24.4) Referent
>35 y
Yes 2 (4.9) 12 (6.2) 0.80 (0.21–2.99) 0.742
No
 39 (95.1)
 181 (93.8)
 Referent
Educational level†
Basic or lower 40 (97.6) 185 (95.9) 1.60 (0.24–10.37) 0.605
Postsecondary
 1 (2.4)
 8 (4.1)
 Referent
Socioeconomical stratum‡
1: low-low 41 (100) 184 (95.3) NA (NA) 0.158
2: low
 0
 9 (4.7)
 Referent
Residential area
Rural 0 7 (3.6) NA (NA) 0.215
Urban
 41 (100)
 186 (96.4)
 Referent
Ethnicity
Afro-Colombian 41 (100) 193 (100) NA (NA) NA
Other
 0
 0
 Referent
Occupation
Head of household§ 33 (80.5) 155 (80.3) 1.00 (0.50–2.03) 0.979
Other
 8 (19.5)
 38 (19.7)
 Referent
Marital status
Single 11 (26.8) 46 (23.8) 1.13 (0.61–2.12) 0.684
With partner¶
 30 (73.2)
 147 (76.2)
 Referent
History of >3 pregnancies
Yes 11 (26.8) 76 (39.4) 0.61 (0.32–1.17) 0.131
No
 30 (73.2)
 117 (60.6)
 Referent
History of spontaneous abortions
Yes 9 (22.0) 40 (20.7) 1.06 (0.54–2.07) 0.860
No
 32 (78.0)
 153 (79.3)
 Referent
History of stillbirths
Yes 1 (2.4) 8 (4.1) 0.62 (0.09–4.05) 0.605
No
 40 (97.6)
 185 (95.9)
 Referent
Trimester of access to PCP
Second or third 22 (53.7) 87 (45.1) 1.32 (0.76–2.31) 0.317
First
 19 (46.3)
 106 (54.9)
 Referent
Lack of syphilis treatment#
Yes 17 (41.5) 16 (8.3) 4.31 (2.62–7.12) <0.001
No 24 (58.5)
 177 (91.7)
 Referent

*Values are no. (%) except as indicated. BPG, benzathine penicillin G; PCP, prenatal care program; RR, relative risk. †Basic or lower: completed secondary school or lower; postsecondary: technical, university, or higher. ‡Socioeconomic stratum scale in Colombia: 1 to 6, with 1 being the lowest level. §Person, whether single or married, who bears the ongoing responsibility for providing financial or social support to their dependents. ¶De facto marriage or married. #Lack of >1 dose of BPG >30 d before delivery.

Main Article

1These first authors contributed equally to this article.

Page created: March 22, 2024
Page updated: April 25, 2024
Page reviewed: April 25, 2024
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