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Volume 30, Number 6—June 2024
Synopsis

Electronic Health Record–Based Algorithm for Monitoring Respiratory Virus–Like Illness

Noelle M. CocorosComments to Author , Karen Eberhardt, Vu-Thuy Nguyen, Catherine M. Brown, Alfred DeMaria, Lawrence C. Madoff, Liisa M. Randall, and Michael Klompas
Author affiliations: Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA (N.M. Cocoros, V.-T. Nguyen, M. Klompas); Harvard Medical School, Boston (N.M. Cocoros, M. Klompas); Commonwealth Informatics, Waltham, Massachusetts, USA (K. Eberhardt); Massachusetts Department of Public Health, Boston (C.M. Brown, A. DeMaria, L.C. Madoff, L.M. Randall); Brigham and Women’s Hospital, Boston (M. Klompas)

Main Article

Table 2

ICD-10 diagnosis codes that met the positive predictive value threshold for confirmed respiratory viral illnesses and are included in the RAVIOLI algorithm for monitoring respiratory virus–like illness*

Virus ICD-10 codes† Description
Adenovirus A08.2 Adenoviral enteritis
B34.0 Adenovirus infection, unspecified
B97.0 Adenovirus as the cause of diseases classified elsewhere

J12.0
Adenoviral pneumonia
Non–SARS-CoV-2 coronavirus
B34.2
Coronavirus infection, unspecified
SARS-CoV-2 B34.2 Coronavirus infection, unspecified
B97.29 Other coronavirus as the cause of diseases classified elsewhere
J12.82 Pneumonia associated with coronavirus disease 2019
J12.89 Other viral pneumonia
J80 Acute respiratory distress syndrome
R05.1 Acute cough
R48.1 Agnosia

U07.1
COVID-19
Human metapneumovirus B97.81 Human metapneumovirus as the cause of diseases classified elsewhere
J12.3 Human metapneumovirus pneumonia

J21.1
Acute bronchiolitis associated with human metapneumovirus
Influenza J09.X1 Influenza from identified novel influenza A virus with pneumonia
J09.X2 Influenza associated with identified novel influenza A virus with other respiratory manifestations
J10.00 Influenza associated with other identified influenza virus with unspecified type of pneumonia
J10.1 Influenza associated with other identified influenza virus with other respiratory manifestations
J11.00 Influenza associated with unidentified influenza virus with unspecified type of pneumonia

J11.1
Influenza associated with unidentified influenza virus with other respiratory manifestations
Parainfluenza B33.8 Other specified viral diseases
B34.8 Other viral infections of unspecified site

J20.4
Acute bronchitis associated with parainfluenza virus
Rhinovirus and enterovirus B34.0 Adenovirus infection, unspecified
B34.8 Other viral infections of unspecified site
B97.10 Unspecified enterovirus as the cause of diseases classified elsewhere
J20.6 Acute bronchitis associated with rhinovirus

J45.902
Unspecified asthma with status asthmaticus
Respiratory syncytial virus B97.4 Respiratory syncytial virus as the cause of diseases classified elsewhere
J12.1 Respiratory syncytial virus pneumonia
J20.5 Acute bronchitis associated with respiratory syncytial virus

J21.0
Acute bronchiolitis associated with respiratory syncytial virus
Any respiratory viral test (nonspecific)
J21.8 Acute bronchiolitis associated with other specified organisms
R06.03 Acute respiratory distress
P81.9 Disturbance of temperature regulation of newborn, unspecified
J12.9 Viral pneumonia, unspecified
R50.81 Fever manifesting with conditions classified elsewhere
J96.90 Respiratory failure, unspecified, unspecified whether with hypoxia or hypercapnia
R05.9 Cough, unspecified
J96.91 Respiratory failure, unspecified with hypoxia
J96.92 Respiratory failure, unspecified with hypercapnia
R57.9 Shock, unspecified

*Respiratory virus-like illness is defined as a clinical encounter with a positive laboratory test result for a respiratory virus listed in Table 1; 1 of the ICD-10 diagnosis codes listed in this table; or a measured fever >100°F. ICD-10, International Classification of Diseases, 10th Revision. †All of the diagnosis codes in the table had a positive predictive value ≥10% PPV for either any positive respiratory virus laboratory test or 1 of the virus-specific positive tests.

Main Article

Page created: April 11, 2024
Page updated: May 22, 2024
Page reviewed: May 22, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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