Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China
Yang Liu
1, Yuhua Chen
1, Zhiyi Yang, Yaozhong Lin, Siyuan Fu, Junhong Chen, Lingyu Xu, Tengfei Liu, Beibei Niu, Qiuhong Huang, Haixia Liu, Chaofeng Zheng, Ming Liao
, and Weixin Jia
Author affiliations: South China Agricultural University, Guangzhou, China (Y. Liu, Z. Yang, Y. Lin, S. Fu, J. Chen, L. Xu, T. Liu, B. Niu, Q. Huang, M. Liao, W. Jia); Guangzhou Animal Health Inspection Institute, Guangzhou (Y. Chen); Guangdong Aib Polytechnic College, Guangzhou (H. Liu); Animal Husbandry and Veterinary Station, Urumqi, China (C. Zheng)
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Figure 1
Figure 1. Phylogenetic analysis of evolution and antigenic differentiation of avian influenza A(H7N9) virus, China. Colors in columns at left show locations, timeframes, hosts, and pathogenicity of virus strains. The maximum-likelihood phylogenetic tree of the hemagglutinin gene depicts viruses corresponding to epidemic waves 1–5. Tree on right shows detail of Group.y.2.3 (red rectangles) and Group.y.2.4.4 (red circles) in comparison with vaccine strains. Scale bar indicates nucleotide substitutions per site. LPAI, low-pathogenicity avian influenza; HPAI, highly pathogenic avian influenza; Other-N, sites in the northern region; Other-S, sites in the southern region.
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