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Volume 30, Number 6—June 2024

Dispatch

Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China

Yang Liu1, Yuhua Chen1, Zhiyi Yang, Yaozhong Lin, Siyuan Fu, Junhong Chen, Lingyu Xu, Tengfei Liu, Beibei Niu, Qiuhong Huang, Haixia Liu, Chaofeng Zheng, Ming LiaoComments to Author , and Weixin JiaComments to Author 
Author affiliations: South China Agricultural University, Guangzhou, China (Y. Liu, Z. Yang, Y. Lin, S. Fu, J. Chen, L. Xu, T. Liu, B. Niu, Q. Huang, M. Liao, W. Jia); Guangzhou Animal Health Inspection Institute, Guangzhou (Y. Chen); Guangdong Aib Polytechnic College, Guangzhou (H. Liu); Animal Husbandry and Veterinary Station, Urumqi, China (C. Zheng)

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Figure 2

Antigenic map of avian influenza A(H7N9) virus, China, 2021–2023. The map was plotted using hemagglutinin inhibition assay results of 26 antigens (green, blue, and yellow dots), serum from 2 vaccine virus strains, H7N9-Re4 and rHN7901 (purple dots), and in-house designed serum of 4 circulating viruses (CK for chicken). The antigen map was constructed using the online website of the Antigenic Cartography Group, University of Cambridge (https://acmacs-web.antigenic-cartography.org). A/Chicken/HeB/257-3/2022 and A/Chicken/HeB/229-2/2022 belong to the Group.y.2.3 branch, whereas A/Chicken/HeB/320-1/2022 and A/Chicken/HeB/363-4/2022 belong to the Group.y.2.4 branch (indicated by white dots). The distance between the figures represents the antigen distance.

Figure 2. Antigenic map of avian influenza A(H7N9) virus, China, 2021–2023. The map was plotted using hemagglutinin inhibition assay results of 26 antigens (green, blue, and yellow dots), serum from 2 vaccine virus strains, H7N9-Re4 and rHN7901 (purple dots), and in-house designed serum of 4 circulating viruses (CK for chicken). The antigen map was constructed using the online website of the Antigenic Cartography Group, University of Cambridge (https://acmacs-web.antigenic-cartography.org). A/Chicken/HeB/257-3/2022 and A/Chicken/HeB/229-2/2022 belong to the Group.y.2.3 branch, whereas A/Chicken/HeB/320-1/2022 and A/Chicken/HeB/363-4/2022 belong to the Group.y.2.4 branch (indicated by white dots). The distance between the figures represents the antigen distance.

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1These first authors contributed equally to this article.

Page created: April 03, 2024
Page updated: May 22, 2024
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