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Volume 30, Number 8—August 2024
Research Letter

Fecal Microbiota Transplantation for Severe Infant Botulism, China

Chaonan Fan1, Rubo Li1, Lijuan Wang, Kechun Li, Xinlei Jia, Hengmiao Gao, Bike Zhang, Xuefang XuComments to Author , and Suyun QianComments to Author 
Author affiliations: Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China (C. Fan, R. Li, L. Wang, K. Li, X. Jia, H. Gao, S. Qian); National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Diseases Control and Prevention, Center for Disease Control and Prevention, Infectious Disease Prevention and Control Institute, Beijing (B. Zhang, X. Xu)

Main Article

Table

Analysis of Clostridium botulinum and botulinum neurotoxin in 4-month-old boy with infant botulism, Beijing, China*

Fecal sample no. Days after admission Sample classification Real-time PCR result Isolated
strain
Mouse bioassay result
A1 3 Before FMT BoNTB B BoNTB
A2 23 Before FMT BoNTB B BoNTB
A3 27 Before FMT BoNTB B BoNTB
A4 32 Before FMT BoNTB B BoNTB
A5 33 Before FMT BoNTB B BoNTB
A6 34 FMT1 Negative B Negative
A7 36 FMT3 Negative Negative Negative
A8 37 FMT4 Negative Negative Negative
A9 38 After FMT Negative Negative Negative
A10 39 After FMT Negative Negative Negative
A11 182 Follow-up Negative Negative Negative

*BoNTB, Clostridium botulinum neurotoxin B; FMT, fecal microbiota transplantation.

Main Article

1These authors contributed equally to this article.

Page created: June 14, 2024
Page updated: July 22, 2024
Page reviewed: July 22, 2024
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