Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.

Volume 30, Number 8—August 2024
Research

Detection of Nucleocapsid Antibodies Associated with Primary SARS-CoV-2 Infection in Unvaccinated and Vaccinated Blood Donors

Eduard Grebe1Comments to Author , Mars Stone1, Bryan R. Spencer, Akintunde Akinseye, David Wright, Clara Di Germanio, Roberta Bruhn, Karla G. Zurita, Paul Contestable, Valerie Green, Marion C. Lanteri, Paula Saa, Brad J. Biggerstaff, Melissa M. Coughlin, Steve Kleinman, Brian Custer, Jefferson M. Jones, and Michael P. Busch
Author affiliations: Vitalant Research Institute, San Francisco, California, USA (E. Grebe, M. Stone, C. Di Germanio, R. Bruhn, K.G. Zurita, B. Custer, M.P. Busch); University of California, San Francisco (M. Stone, R. Bruhn, M.C. Lanteri, B. Custer, M.P. Busch); American Red Cross, Rockville, Maryland, USA (B.R. Spencer, P. Saa); Westat, Rockville (A. Akinseye, D. Wright); QuidelOrtho, Rochester, New York, USA (P. Contestable); Creative Testing Solutions, Tempe, Arizona, USA (V. Green, M.C. Lanteri); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (B.J. Biggerstaff); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.M. Coughlin, J.M. Jones); University of British Columbia, Vancouver, British Columbia, Canada (S. Kleinman)

Main Article

Figure 2

Factors influencing nucleocapsid antibody seroconversion after swab-confirmed first SARS-CoV-2 infections among vaccinated and unvaccinated blood donors, United States, July 2021–December 2022. ORs and 95% CIs from logistic regression are shown. In the multivariable regression model (adjusted ORs), the categories for certain variables have been grouped together; the vaccination status at the time of infection and timing of most recent vaccine before infection were combined in the vaccination status or timing variable, and in the variable for time from infection to tested sample, the groups for samples collected 7–12 months and >1 year postinfection were combined. Number of samples in each group, the proportion of nucleocapsid antibody–reactive samples, and ORs are shown in Appendix Table 2. OR, odds ration; ref, reference variable.

Figure 2. Factors influencing nucleocapsid antibody seroconversion after swab-confirmed first SARS-CoV-2 infections among vaccinated and unvaccinated blood donors, United States, July 2021–December 2022. ORs and 95% CIs from logistic regression are shown. In the multivariable regression model (adjusted ORs), the categories for certain variables have been grouped together; the vaccination status at the time of infection and timing of most recent vaccine before infection were combined in the vaccination status or timing variable, and in the variable for time from infection to tested sample, the groups for samples collected 7–12 months and >1 year postinfection were combined. Number of samples in each group, the proportion of nucleocapsid antibody–reactive samples, and ORs are shown in Appendix Table 2. OR, odds ration; ref, reference variable.

Main Article

1These first authors contributed equally to this article.

Page created: June 10, 2024
Page updated: July 09, 2024
Page reviewed: July 09, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external