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Volume 31, Number 1—January 2025
Research Letter

Low IgG Seroconversion among Persons Vaccinated against Measles, Republic of Congo

Yanne Vanessa Thiécesse Mavoungou, Léa Gwladys Gangoué, Félix Koukouikila-Koussounda, Cynthia Badzi Nkoua, Pembe Issamou Mayengue, Jean-Medard Kankou, Pathou Christelle Kiminou, Princesse Mahoukou, Louis Régis Dossou-Yovo, Gabriel Ahombo, and Fabien Roch NiamaComments to Author 
Author affiliation: Laboratoire National de Santé Publique, Brazzaville, Republic of Congo (Y.V.T. Mavoungou, L.G. Gangoué, F. Koukouikila-Koussounda, C. Badzi Nkoua, P.I. Mayengue, P.C. Kiminou, P. Mahoukou, L.R. Dossou-Yovo, F.R. Niama); Université Marien Ngouabi, Brazzaville (Y.V.T. Mavoungou, L.G. Gangoué, F. Koukouikila-Koussounda, C. Badzi Nkoua, P.I. Mayengue, G. Ahombo, F.R. Niama); Direction of Epidemiology and Disease Control, Brazzaville (J.-M. Kankou)

Main Article

Table

IgG seroconversion status in study of low IgG seroconversion among persons vaccinated against measles, Republic of Congo*

Variables IgG positive IgG negative p value
Total no. patients
 74 (38.7)
 117 (61.3)
 <0.0001
Age group, y
Median age (IQR) 5 (3–7) 4 (2–6) 0.3956
˂5 36 (35.6) 65 (64.4) <0.0001
5–9 26 (40) 39 (60) 0.0226
>10
 12 (48)
 13 (52)
 0.7773
Patient sex
M 34 (39.1) 53 (60.9) 0.004
F
 40 (38.5)
 64 (61.5)
 0.0009
Vaccination status
1 dose 57 (38) 93 (62) <0.0001
>2 doses
 17 (41.5)
 24 (58.5)
 0.1221
Interval between last vaccination and disease onset, mo
Median interval (interquartile range) 30 (5–60) 19 (3–51) 0.1957
Unknown 9 (31) 20 (69) 0.0039
2–48 42 (37.8) 69 (62.2) 0.0003
>48–108 15 (38.5) 24 (61.5) 0.0415
>108
 8 (66.7)
 4 (33.3)
 0.1025
Municipality
Urban 43 (33.6) 85 (66.4) <0.0001
Rural 31 (49.2) 32 (50.8) 0.8586

*Values are no. (%) except as indicated.

Main Article

Page created: October 30, 2024
Page updated: December 13, 2024
Page reviewed: December 13, 2024
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