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Volume 31, Number 10—October 2025

Dispatch

Emergence of Bordetella holmesii–Associated Pertussis-Like Illness, Northern India, 2019–2023

Nishant Shekhar, Deepa Sharma, Surajit Chakraborty, Rajesh Kumar, Rajneesh Singh Rawat, Nirmal Kaundal, Pawan Kumar, Tigran Avagyan, Deeksha Chauhan, Neha Jain, Megha Sharma, Arun Kumar, and Vikas GautamComments to Author 
Author affiliation: Post Graduate Institute of Medical Education and Research, Chandigarh, India (N. Shekhar, R. Kumar, R.S. Rawat, D. Chauhan, V. Gautam); World Health Organization Country Office India, New Delhi, India (D. Sharma, N. Kaundal, T. Avagyan); University of Miami Miller School of Medicine, Miami, Florida, USA (S. Chakraborty); India Ministry of Health and Family Welfare, New Delhi (P. Kumar); Yatharth Hospital, Noida, India (N. Jain); All India Institute of Medical Science−Bilaspur, Bilaspur, India (M. Sharma)

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Figure

Yearwise trend of Bordetella pertussis and B. holmesii positivity from study of emergence of B. holmesii–associated pertussis-like illness, northern India, 2019–2023. Data based on real-time quantitative PCR using the IS481-ptxS1-hIS1001 gene profile. Positiviity is shown overall and for 2 cohorts: group I (n = 213), patients hospitalized with acute respiratory illness at Postgraduate Institute of Medical Education and Research’s Advanced Pediatric Center; and group II (n = 722), obtained through the Vaccine-Preventable Disease Surveillance Network according to guidelines (9).

Figure. Yearwise trend of Bordetella pertussis and B. holmesii positivity from study of emergence of B. holmesii–associated pertussis-like illness, northern India, 2019–2023. Data based on real-time quantitative PCR using the IS481-ptxS1-hIS1001 gene profile. Positiviity is shown overall and for 2 cohorts: group I (n = 213), patients hospitalized with acute respiratory illness at Postgraduate Institute of Medical Education and Research’s Advanced Pediatric Center; and group II (n = 722), obtained through the Vaccine-Preventable Disease Surveillance Network according to guidelines (9).

Main Article

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