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Volume 31, Number 10—October 2025

Research

Prolonged Monkeypox Virus Infections, California, USA, May 2022–August 2024

Samuel SchildhauerComments to Author , Kayla Saadeh, Robert E. Snyder, Eric C. Tang, Eric Chapman, Deanna A. Sykes, Philip Peters, Kathleen Jacobson, Jessica Watson, and Kelly A. Johnson
Author affiliation: University of California School of Medicine, Davis, California (S. Schildhauer); California Department of Public Health, Richmond, California, USA (S. Schildhauer, K. Saadeh, E.C. Tang, K. Jacobson, J. Watson, K.A. Johnson); California Department of Public Health, Sacramento, California, USA (R.E. Snyder, E. Chapman, D.A. Sykes, P. Peters); University of California, San Francisco, California, USA (K.A. Johnson)

Main Article

Table 3

CD4 count and viral load among 2,599 persons with HIV among patients with prolonged and nonprolonged monkeypox virus infections, California, USA, May 12, 2022–August 31, 2024

Value Prolonged
 Nonprolonged
 Total
No. % (95% CI) No. % (95% CI) No. % (95% CI)
CD4 count
<200 5 10.0 (3.33–21.81) 100 3.9 (3.24–4.75) 105 4.0 (3.35–4.87)
200–499 8 16.0 (7.17–29.11) 514 20.2 (18.65–21.77) 522 20.1 (18.59–21.67)
>500* 14 28.0 (16.23–42.49) 1,474 57.8 (55.9–59.73) 1,488 57.3 (55.34–59.14)
Out of care*
 23
 46.0 (31.81–60.68)
461
 18.1 (16.64–19.63)
484
 18.6 (17.17–20.17)
Viral load
<200* 21 42.0 (28.19–56.79) 1,836 72.0 (70.25–73.74) 1,857 71.5 (69.68–73.15)
>200 6 12.0 (4.53–24.31) 228 8.9 (7.9–10.12) 234 9.0 (7.96–10.17)
Out of care*
 23
 46.0 (31.81–60.68)
485
 19.0 (17.55–20.6)
508
 19.5 (18.07–21.12)
Total 50 2,549 2,599

*Indicates nonoverlapping 95% CIs (statistical significance).

Main Article

Page created: August 18, 2025
Page updated: September 25, 2025
Page reviewed: September 25, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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