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Volume 31, Number 11—November 2025

Research Letter

Molecular Evidence of Dengue Virus Serotype 2 in Travelers Returning to Israel from the Sinai Peninsula

Neta S. Zuckerman1Comments to Author , Guy Choshen1, Yaniv Lustig, Anna Shoykhet, Keren Friedman, Tatyana Kushnir, Ora Halutz, Hovav Azulay, Victoria Indenbaum1, and Eli Schwartz1
Author affiliation: Sheba Medical Center, Ramat-Gan, Israel (N.S. Zuckerman, Y. Lustig, K. Friedman, T. Kushnir, V. Indenbaum, E. Schwartz); Tel-Aviv University, Tel Aviv, Israel (G. Choshen, Y. Lustig, O. Halutz, E. Schwartz); Meir Medical Center, Kfar-Saba, Israel (G. Choshen, A. Shoykhet); Infectious Disease Institute, Soroka University Medical Center, Beer Sheba, Israel (H. Azulay)

Main Article

Table

Epidemiology and test results of patients in study of molecular evidence of DENV-2 emergence from travelers returning to Israel from the Sinai Peninsula*

Characteristic Patient 1 Patient 2 Patient 3 Patient 4
Patient age, y/sex
33/M
40/F
45/M
19/M
DENV laboratory diagnostic analysis
Sample collection date 2024 Apr 22 2024 May 7 2024 Jun 5 2024 Jun 10
Serum quantitative real-time PCR DENV-2 (Ct 28) DENV-2 (Ct 26.5) DENV-2 (Ct 27) DENV-2 (Ct 34)
Serum EIA IgM Negative Negative Positive Positive
Serum EIA IgG Negative Negative Positive Negative
DENV nonstructural protein 1 antigen Positive Positive Negative Positive

*Ct, cycle threshold; DENV, dengue virus; DENV-2, DENV serotype 2; EIA, enzyme immunoassay.

Main Article

1These authors contributed equally to this article.

Page created: September 18, 2025
Page updated: December 04, 2025
Page reviewed: December 04, 2025
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