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Volume 31, Number 4—April 2025
Dispatch

Alpha-Gal Syndrome after Ixodes scapularis Tick Bite and Statewide Surveillance, Maine, USA, 2014–2023

Eleanor F. Saunders1, Haris Sohail1, Devin J. Myles, Dawn Charnetzky, Bryan N. Ayres, William L. Nicholson, Scott P. Commins, and Johanna S. SalzerComments to Author 
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E.F. Saunders, B.N. Ayres, W.L. Nicholson, J.S. Salzer); University of North Carolina, Chapel Hill, North Carolina, USA (E.F. Saunders, S.P. Commins); Maine Center for Disease Control and Prevention, Augusta, Maine, USA (H. Sohail, D.J. Myles); MCD Global Health, Hallowell, Maine, USA (D.J. Myles); Maine Medical Center, Portland, Maine, USA (D. Charnetzky)

Main Article

Table 1

Retrospective details from a patient with alpha-gal syndrome after Ixodes scapularis tick bite, Maine, USA, 2022*

Date Days after tick bite Meal Alcohol, servings Symptoms or clinical testing Timing of symptoms relative to meal, h Persons sharing meal ill
May 13
 9
 Roasted rabbit and vegetables
 1
 Abdominal pain, malaise, substernal ache, difficult concentration
 2–3
 No
May 14
 10
 Portions of ham sub, salami sub, and veal lasagna
 2
 Abdominal pain, malaise, substernal ache, difficult concentration
 2–3
 No
May 15–18
 11–14
 1/2 roast beef sub
 0
 Abdominal pain, malaise, substernal ache, difficult concentration
 2–3
 No
May 15
 11
 Chicken
 0
 None
 NA
 No
May 18
 14
 Fish
 0
 None
 NA
 No
May 20
 16
 Beef, broccoli, rice
 1
 Abdominal pain, diarrhea, vomiting, pain similar to prior food poisoning
 2–3
 No
May 21
 17
 Vegetarian Indian food
 0
 None
 NA
 No
May 23–27
 19–23
 Milkshake
 0
 Abdominal discomfort
 2–3
 NA
May 24
 20
Primary care appointment, α-gal testing sent
May 25
 21
 Deviled egg appetizers
 2
 None
 NA
 No
May 28
 24
 Pork dumplings
 1
 Abdominal pain, malaise, substernal ache, difficult concentration
 2–3
 No
June 1 28 Positive result from May 24 α-gal test

*NA, not applicable (i.e., no symptoms).

Main Article

1These first authors contributed equally to this article.

Page created: February 04, 2025
Page updated: March 19, 2025
Page reviewed: March 19, 2025
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