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Volume 31, Number 5—May 2025
Dispatch
Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024
Table 2
Amino acid differences in influenza A(H1N1)pdm09 viruses with reduced susceptibility to baloxavir, Japan, 2024*
Influenza virus | PA |
PB1 |
PB2 |
HA |
NA |
NS1 |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
38 | 258 | 531 | 617 | 622 | 661 | 152 | 308 | 649 | 6 | 274 | 51 | 383 | 178 | ||||||
A/Yamagata/103/2024 | N | E | K | D | G | T | S | I | I | V | V | E | T | I | |||||
A/Yamagata/333/2023 | T | E | R | N | G | A | A | V | V | I | M | K | T | V | |||||
A/Yamagata/336/2023 | I | K | R | D | R | A | A | V | V | V | M | K | I | V |
*HA, hemagglutinin; NA, neuraminidase; NS1, nonstructural protein 1; PA, polymerase acidic protein; PB1, polymerase basic protein 1; PB2, polymerase basic protein 2.
Page created: March 19, 2025
Page updated: April 03, 2025
Page reviewed: April 03, 2025
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