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Volume 31, Number 5—May 2025
Research Letter

Unexpected Zoonotic and Hybrid Schistosome Egg Excretion Patterns, Malawi, 2024

Angus M. O’Ferrall, Sekeleghe A. Kayuni, Lucas J. Cunningham, Peter Makaula, John Archer, Adam P. Roberts, Janelisa Musaya1, and J. Russell Stothard1Comments to Author 
Author affiliation: Liverpool School of Tropical Medicine, Liverpool, UK (A.M. O’Ferrall, S.A. Kayuni, L.J. Cunningham, J. Archer, A.P. Roberts, J.R. Stothard); Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, Blantyre, Malawi (S.A. Kayuni, P. Makaula, J. Musaya); School of Medicine and Oral Health, Kamuzu University of Health Sciences, Blantyre (S.A. Kayuni, J. Musaya); Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, UK (J. Archer)

Main Article

Table

Summary of diagnostic information for patient X and patient Y from unexpected zoonotic and hybrid schistosome egg excretion patterns, Malawi, 2024*

Diagnostic test Patient X Patient Y
Urinary diagnostics
Eggs/10 mL urine (no. typed)† >50 (71) 30 (50)
Microhematuria Large Large
Visible hematuria Yes Yes
Proteinuria >2,000 mg/dL >2,000 mg/dL
Turbid urine Yes Yes
POC-CCA
 Positive
 Positive
Fecal diagnostics
Eggs/g feces (no. typed)† 84 (60) 240 (34)
Fecal occult blood Negative Positive

*POC-CCA, point-of-care urine circulating cathodic antigen cassette tests. †Miracidia typing.

Main Article

1These senior authors contributed equally to this article.

Page created: March 31, 2025
Page updated: April 17, 2025
Page reviewed: April 17, 2025
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