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Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.

Volume 31, Number 6—June 2025

CME ACTIVITY - Synopsis

Clinical Manifestations, Risk Factors, and Disease Burden of Rickettsiosis, Cambodia, 2007–2020

Gerard C. Kelly, Agus Rachmat, Long Khanh Tran, Chonthida Supaprom, Hip Phireak, Satharath Prom, Heng Sopheab, Nora Cleary, Michael von Fricken, Christina M. Farris, and Andrew G. LetiziaComments to Author 
Author affiliation: Culmen International, LLC, Alexandria, Virginia, USA (G.C. Kelly, L.K. Tran); AC Investment Co, contractor for NAMRU INDO PACIFIC, Phnom Penh, Cambodia (A. Rachmat, C. Supaprom, H. Phireak); Oxford University Clinical Research Unit, Jakarta, Indonesia (A. Rachmat); Cambodia Ministry of National Defense Department of Health, Phnom Penh (S. Prom); Cambodia National Institute of Public Health, Phnom Penh (H. Sopheab); University of Florida College of Public Health and Health Professions, Gainesville, Florida, USA (N. Cleary, M. von Fricken); US Naval Medical Research Command Viral and Rickettsial Diseases Department, Silver Spring, Maryland, USA (C.M Farris); US Naval Medical Research Unit INDO PACIFIC, Singapore (A.G. Letizia)

Main Article

Table 1

Rickettsial infections detected by type and diagnostic method among patients with acute undifferentiated febrile illness tested for rickettsioses at health facilities as part of study of rickettsiosis in Cambodia, 2007–2020*

Group Result Diagnostic method, no. (%) patients
4-fold increase Seroconversion Seroconversion or 4-fold increase
STG Negative 10,211 (99.7) 10,139 (99.0) 10,107 (98.7)
Positive
 32 (0.3)
 104 (1.0)
 136 (1.3)
TG Negative 10,176 (99.3) 9,753 (95.2) 9,686 (94.6)
Positive
 67 (0.7)
 490 (4.8)
 557 (5.4)
SFG Negative 10,221 (99.8) 10,111 (98.7) 10,089 (98.5)
Positive 22 (0.2) 132 (1.3) 154 (1.5)

*SFG, spotted fever group; STG, scrub typhus group; TG, typhus group.

Main Article

Page created: March 18, 2025
Page updated: May 27, 2025
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