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Volume 31, Number 7—July 2025

Research Letter

Next-Generation Sequencing Techniques to Diagnose Culture-Negative Subacute Native Aortic Endocarditis

Delphine Vetterli1, Morgana Zennaro1, Virginie Tacchini, Joannes Alexander Lobrinus, Virginie Prendki, Vladimir Lazarevic, and Jacques SchrenzelComments to Author 
Author affiliation: Geneva University Hospitals Department of Medicine, Geneva, Switzerland (D. Vetterli, M. Zennaro); Geneva University Hospitals Division of Cardiology, Geneva (V. Tacchini); Geneva University Hospitals Department of Pathology, Geneva (J.A. Lobrinus); Geneva University Hospitals Department of Rehabilitation and Geriatrics, Geneva (V. Prendki); Genomic Research Laboratory, Faculty of Medicine, Geneva University, Geneva (V. Lazarevic, J. Schrenzel); Geneva University Hospitals Division of Infectious Diseases, Geneva (V. Prendki, J. Schrenzel); Geneva University Hospitals Bacteriology Laboratory, Geneva (J. Schrenzel)

Main Article

Figure 1

Color doppler echocardiography images from fatal case of subacute native aortic endocarditis, Geneva, Switzerland. A) Mid-esophageal long-axis view during diastole, showing moderate to severe aortic regurgitation. B) Mid-esophageal long-axis view with left ventricular chamber, aortic valve, and aortic root during systole. Red arrow indicates systolic flow with the pseudo-aneurysm. AV, open aortic valve; LA, left atrial; LV, left ventricle.

Figure 1. Color doppler echocardiography images from fatal case of subacute native aortic endocarditis, Geneva, Switzerland. A) Mid-esophageal long-axis view during diastole, showing moderate to severe aortic regurgitation. B) Mid-esophageal long-axis view with left ventricular chamber, aortic valve, and aortic root during systole. Red arrow indicates systolic flow with the pseudo-aneurysm. AV, open aortic valve; LA, left atrial; LV, left ventricle.

Main Article

1These authors are co–first authors.

Page created: May 31, 2025
Page updated: June 20, 2025
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