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Volume 31, Number 7—July 2025

Research Letter

Next-Generation Sequencing Techniques to Diagnose Culture-Negative Subacute Native Aortic Endocarditis

Delphine Vetterli1, Morgana Zennaro1, Virginie Tacchini, Joannes Alexander Lobrinus, Virginie Prendki, Vladimir Lazarevic, and Jacques SchrenzelComments to Author 
Author affiliation: Geneva University Hospitals Department of Medicine, Geneva, Switzerland (D. Vetterli, M. Zennaro); Geneva University Hospitals Division of Cardiology, Geneva (V. Tacchini); Geneva University Hospitals Department of Pathology, Geneva (J.A. Lobrinus); Geneva University Hospitals Department of Rehabilitation and Geriatrics, Geneva (V. Prendki); Genomic Research Laboratory, Faculty of Medicine, Geneva University, Geneva (V. Lazarevic, J. Schrenzel); Geneva University Hospitals Division of Infectious Diseases, Geneva (V. Prendki, J. Schrenzel); Geneva University Hospitals Bacteriology Laboratory, Geneva (J. Schrenzel)

Main Article

Figure 2

Autopsy results from fatal case of subacute native aortic endocarditis, Geneva, Switzerland. A) Autopsy material of the ascendant aorta (1) with the open blood-filled neocavity of 15 × 10 mm (blue arrow) just beneath the perforated noncoronary leaflet of the AV (2) and extending to the valvular ring (3). B) Autopsy material of the open aortic valve with perforated noncoronary leaflet (1), left coronary leaflet (2), and right coronary leaflet (3).

Figure 2. Autopsy results from fatal case of subacute native aortic endocarditis, Geneva, Switzerland. A) Autopsy material of the ascendant aorta (1) with the open blood-filled neocavity of 15 × 10 mm (blue arrow) just beneath the perforated noncoronary leaflet of the AV (2) and extending to the valvular ring (3). B) Autopsy material of the open aortic valve with perforated noncoronary leaflet (1), left coronary leaflet (2), and right coronary leaflet (3).

Main Article

1These authors are co–first authors.

Page created: May 31, 2025
Page updated: June 20, 2025
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