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Volume 31, Number 8—August 2025

Research Letter

Emergence of Novel Fluoroquinolone Resistance Mutations in Mycoplasma bovis, China, 2008–2023

Shimei Lan, Shuang Liu, Wenjing Cui, Zhangcheng Li, Huafang Hao, Ahmed Adel Baz, Jinjia Liang, Xiangrui Jin, Xinmin Yan, Pengcheng Gao, Fuying Zheng, Shengli Chen1Comments to Author , and Yuefeng Chu1Comments to Author 
Author affiliation: State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China (S. Lan, S. Liu, W. Cui, Z. Li, H. Hao, A.A. Baz, J. Liang, X. Jin, X. Yan, P. Gao, F. Zheng, S. Chen, Y. Chu); Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou (S. Lan, S. Liu, Z. Li, H. Hao, A.A. Baz, J. Liang, X. Jin, X. Yan, P. Gao, F. Zheng, S. Chen, Y. Chu); Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou (S. Lan, S. Liu, Z. Li, H. Hao, A.A. Baz, J. Liang, X. Jin, X. Yan, P. Gao, F. Zheng, S. Chen, Y. Chu)

Main Article

Figure 1

Phylogenetic analysis of Mycoplasma bovis in study of emergence of novel fluoroquinolone resistance mutations, China, 2008–2023. Maximum-likelihood tree shows 77 M. bovis isolates according to single-nucleotide polymorphisms identified by referencing the complete genome sequence of M. bovis strain HB0801. Name of isolate, year isolated, province, sequence type, and clustering are indicated. Scale bar indicates nucleotide substitutions per site.

Figure 1. Phylogenetic analysis of Mycoplasma bovis in study of emergence of novel fluoroquinolone resistance mutations, China, 2008–2023. Maximum-likelihood tree shows 77 M. bovis isolates according to single-nucleotide polymorphisms identified by referencing the complete genome sequence of M. bovis strain HB0801. Name of isolate, year isolated, province, sequence type, and clustering are indicated. Scale bar indicates nucleotide substitutions per site.

Main Article

1These senior authors contributed equally to this article.

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