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Volume 31, Number 8—August 2025

CME ACTIVITY - Research

Scheffersomyces spartinae Fungemia among Pediatric Patients, Pakistan, 2020–2024

Kauser Jabeen, Joveria Farooqi, Lacy M. Simons, Judd F. Hultquist, Ramon Lorenzo-Redondo, Charlesnika T. Evans, Erica M. Hartmann, Mohammad Hanif, Zahra Hasan, Syed Faisal Mahmood, Javaria Ashraf, Hassan Ghayas, Sadaf Zaka, Noureen Saeed, Sayed Ali Raza Shah Bukhari, Mehreen Arshad, Larry K. Kociolek, Sameer J. Patel, Rumina Hasan, and Egon A. OzerComments to Author 
Author affiliation: Aga Khan University, Karachi, Pakistan (K. Jabeen, J. Farooqui, Z. Hasan, S.F. Mahmood, J. Ashraf, H. Ghayas, S. Zaka, N. Saeed, S.A.R. Shah Buhari, M. Arshad, R. Hasan); Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA (L.M. Simons, J.F. Hultquist, R. Lorenzo-Redondo, C.T. Evans, E.M. Hartmann, E.A. Ozer); Northwestern University Havey Institute for Global Health, Chicago (L.M. Simons, J.F. Hultquist, R. Lorenzo-Redondo, E.A. Ozer); Edward Hines Jr. VA Hospital, Hines, Illinois, USA (C.T. Evans); Northwestern University McCormick School of Engineering, Evanston, Illinois, USA (E.M. Hartmann); National Institute of Child Health, Karachi (M. Hanif); Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago (M. Arshad, L.K. Kociolek, S.J. Patel); London School of Hygiene and Tropical Medicine, London, UK (R. Hasan)

Main Article

Figure 3

Whole-genome phylogeny and locations of Scheffersomyces spartinae fungemia isolates among pediatric patients, Pakistan, 2020–2024. A) Midpoint-rooted maximum-likelihood phylogenetic tree from whole-genome sequence alignment of 108 S. spartinae isolates from human blood cultures. Tip circles indicate the patient’s city of residence. Outer squares indicate the age of the patient. Arcs indicate observed major phylogenetic clades or subclades. Scale bar indicates number of single-nucleotide variant differences corresponding to branch lengths. B) Cities of residence for all patients with S. spartinae–positive blood cultures detected by whole-genome sequencing.

Figure 3. Whole-genome phylogeny and locations of Scheffersomyces spartinae fungemia isolates among pediatric patients, Pakistan, 2020–2024. A) Midpoint-rooted maximum-likelihood phylogenetic tree from whole-genome sequence alignment of 108 S. spartinae isolates from human blood cultures. Tip circles indicate the patient’s city of residence. Outer squares indicate the age of the patient. Arcs indicate observed major phylogenetic clades or subclades. Scale bar indicates number of single-nucleotide variant differences corresponding to branch lengths. B) Cities of residence for all patients with S. spartinae–positive blood cultures detected by whole-genome sequencing.

Main Article

Page created: June 02, 2025
Page updated: July 24, 2025
Page reviewed: July 24, 2025
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