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Volume 31, Number 8—August 2025

CME ACTIVITY - Research

Scheffersomyces spartinae Fungemia among Pediatric Patients, Pakistan, 2020–2024

Kauser Jabeen, Joveria Farooqi, Lacy M. Simons, Judd F. Hultquist, Ramon Lorenzo-Redondo, Charlesnika T. Evans, Erica M. Hartmann, Mohammad Hanif, Zahra Hasan, Syed Faisal Mahmood, Javaria Ashraf, Hassan Ghayas, Sadaf Zaka, Noureen Saeed, Sayed Ali Raza Shah Bukhari, Mehreen Arshad, Larry K. Kociolek, Sameer J. Patel, Rumina Hasan, and Egon A. OzerComments to Author 
Author affiliation: Aga Khan University, Karachi, Pakistan (K. Jabeen, J. Farooqui, Z. Hasan, S.F. Mahmood, J. Ashraf, H. Ghayas, S. Zaka, N. Saeed, S.A.R. Shah Buhari, M. Arshad, R. Hasan); Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA (L.M. Simons, J.F. Hultquist, R. Lorenzo-Redondo, C.T. Evans, E.M. Hartmann, E.A. Ozer); Northwestern University Havey Institute for Global Health, Chicago (L.M. Simons, J.F. Hultquist, R. Lorenzo-Redondo, E.A. Ozer); Edward Hines Jr. VA Hospital, Hines, Illinois, USA (C.T. Evans); Northwestern University McCormick School of Engineering, Evanston, Illinois, USA (E.M. Hartmann); National Institute of Child Health, Karachi (M. Hanif); Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago (M. Arshad, L.K. Kociolek, S.J. Patel); London School of Hygiene and Tropical Medicine, London, UK (R. Hasan)

Main Article

Table 2

MICs of 108 isolates from Scheffersomyces spartinae fungemia among pediatric patients, Pakistan, 2020–2024*

Antifungal drug MIC, µg/mL
Detected range MIC50 MIC90
Fluconazole 0.06–16 0.5 1
Itraconazole 0.015–2 0.06 0.12
Voriconazole 0.008–1 0.03 0.03
Posaconazole 0.008–1 0.03 0.06
Flucytosine 0.06–64 32 64
Amphotericin 0.03–0.5 0.12 0.25
Caspofungin 0.015–0.5 0.06 0.12
Anidulafungin 0.015–0.5 0.12 0.12
Micafungin 0.015–0.25 0.06 0.12

*MIC50, concentration required to inhibit 50% of strains; MIC90, concentration required to inhibit 90% of strains.

Main Article

Page created: June 02, 2025
Page updated: July 24, 2025
Page reviewed: July 24, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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