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Volume 32, Number 1—January 2026

Research

Clinical Manifestations of Emerging Trichosporon spp. Infections, France

Marie Desnos-OllivierComments to Author , Alexandre Alanio, Maud Gits-Muselli, Karine Boukris-Sitbon, Agathe Bertho, Aude Sturny-Leclère, Emilie Guemas, Philippe Poirier, Christine Bonnal, Marie-Elisabeth Bougnoux, Sophie Brun, Taieb Chouaki, Nicole Desbois-Nogard, Elisabeth Chachaty, Florence Persat, Marc Pihet, André Paugam, Françoise Botterel, Magalie Demar, Loïc Favennec, Florent Morio, Frédéric Gabriel, Arnaud Fekkar, Jean-Pierre Gangneux, Caroline Mahinc, Valérie Letscher-Bru, Laurence Millon, Frédéric Dalle, Julie Bonhomme, Muriel Nicolas, Boualem Sendid, Milène Sasso, Laure Courtellemont, Anne-Laure Roux, Estelle Perraud-Cateau, Juliette Guitard, Edith Mazars, Olivier Lortholary, and Fanny Lanternier
Author affiliation: Institut Pasteur, Paris, France (M. Desnos-Ollivier, A. Alanio, K. Boukris-Sitbon, A. Bertho, A. Sturny-Leclère, O. Lortholary, F. Lanternier); Hôpital Saint-Louis, Paris (A. Alanio); Hôpital Robert Debré, APHP, Université Paris Cité, Paris (M. Gits-Muselli); Université Paris Cité, INSERM, IAME, Paris (M. Gits-Muselli); Centre National de la Recherche Scientifique, Toulouse, France (E. Guemas); Centre Hospitalier Universitaire Clermont-Ferrand, Clermont-Ferrand, France (P. Poirier); Université Blaise Pascal, Clermont-Ferrand (P. Poirier); Hôpital Bichat–Claude-Bernard, Paris (C. Bonnal); Hôpital Necker-Enfants Malades, Paris (M.-E. Bougnoux, O. Lortholary, F. Lanternier); Hôpital Avicenne, Bobigny, France (S. Brun); Centre Hospitalier Universitaire Amiens-Picardie, Amiens, France (T. Chouaki); University Hospital of Martinique, Fort-de-France, Martinique (N. Desbois-Nogard); Gustave Roussy, Villejuif, France (E. Chachaty); Centre Hospitalier Universitaire de Lyon, Lyon, France (F. Persat); CHU d'Angers, University Angers, University Brest, GEIHP, SFR ICAT, Angers, France (M. Pihet); Cochin Port Royal University Hospital AP-AP, Paris (A. Paugam); Université Paris-Est Créteil, Créteil, France (F. Botterel); Centre Hospitalier Andree Rosemon, Cayenne, Guyana (M. Demar); University Hospital Charles Nicolle, Rouen, France (L. Favennec); Nantes University Hospital, Nantes, France (F. Morio); Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France (F. Gabriel); Centre d’Immunologie et des Maladies Infectieuses, Paris (A. Fekkar); Hôpital Pontchaillou, Rennes, France (J.-P. Gangneux); Centre Hospitalier Universitaire de Saint-Etienne, Saint-Etienne, France (C. Mahinc); Hôpitaux Universitaires de Strasbourg, Strasbourg, France (V. Letscher-Bru); University Hospital J Minjoz, Besancon, France (L. Millon); Dijon University Hospital, Dijon, France (F. Dalle); Centre Hospitalier Universitaire Côte de Nacre, Caen, France (J. Bonhomme); Centre Hospitalier Universitaire de Guadeloupe, Pointe-à-Pitre, Guadeloupe, France (M. Nicolas); Lille University Hospital Center, Lille, France (B. Sendid); Centre Hospitalier Universitaire Nîmes et Université de Montpellier, Nîmes, France (M. Sasso); Centre Hospitalier Universitaire d’Orléans, Orléans, France (L. Courtellemont); Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France (A.-L. Roux); Centre Hospitalier Universitaire Poitiers, Poitiers, France (E. Perraud-Cateau); Hôpital Saint-Antoine, Paris (J. Guitard); Centre Hospitalier de Valenciennes, Valenciennes, France (E. Mazars)

Main Article

Table 1

Demographic and clinical characteristics of patients in study of clinical manifestations of emerging Trichosporon species infections, France, 2002–2022*

Characteristics
 Value
Sex
M
 74 (66.1)
F
 38 (33.9
Age, years, mean ±SD (range)
 43.77 ±24.39 (1–90)
<15 y
 21 (18.8)
>65 y
 20 (17.7)
Clinical information
Bloodstream infection
 87 (77.7)
Bone infection
 12 (10.7)
Stay in intensive care unit, n = 98
 45 (45.9)
Underlying conditions
Hematologic malignancy
 44 (39.3)
Acute leukemia
 25
Lymphoma
 13
Recent surgery
 32 (28.6)
Solid organ transplantation
 14 (11.6)
Kidney
 5
Heart
 4
Liver
 4
Lung
 1
Diabetes
 12 (10.7)
Risk factors
Neutropenia
 23 (20.5)
Presence of catheter
 63 (56.3)
Immunosuppressive treatment
 42 (37.5)
Steroids
 25 (22.3)
Antifungal exposure
 38 (33.9)
Echinocandins
 27 (24.1)
Antifungal treatment
 101 (90.2)
Containing voriconazole
 64 (57.1)
Containing amphotericin B
 24 (21.4)
Outcome, n = 99
Death within 30 days of diagnosis 38 (38.4)

*Values are no. (%) except as indicated.

Main Article

Page created: December 30, 2025
Page updated: January 29, 2026
Page reviewed: January 29, 2026
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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