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Volume 32, Number 1—January 2026

Dispatch

Disseminated Nocardia ignorata Infection with Splenic and Brain Involvement in Patient with Large B-Cell Lymphoma

Sherif Elbaz, Mahmoud IsmailComments to Author , Seth Glassman, Asmaa Badr, and Eric John Dove
Author affiliation: University at Buffalo, Buffalo, New York, USA (S. Elbaz, M. Ismail, S. Glassman, E.J. Dove); The Ohio State University, Columbus, Ohio, USA (A. Badr)

Main Article

Figure 3

Brain tissue images from 79-year-old man with chronic obstructive pulmonary disease and large B-cell lymphoma who had disseminated Nocardia ignorata infection, United States. A, B) Parenchyma with identifiable granulation tissue, neutrophils, and histocytes and background hemorrhage and necrosis are seen. Hematoxylin and eosin stain; original magnification ×10. C–F) Thin, filamentous, partially acid-fast rods with a beaded appearance within the necrotic tissue background are visible. Branching within visualized organisms was not identified. Arrows indicate N. ignorata bacteria. Fite–Faraco stain; original magnification × 100.

Figure 3. Brain tissue images from 79-year-old man with chronic obstructive pulmonary disease and large B-cell lymphoma who had disseminated Nocardia ignorata infection, United States. A, B) Parenchyma with identifiable granulation tissue, neutrophils, and histocytes and background hemorrhage and necrosis are seen. Hematoxylin and eosin stain; original magnification ×10. C–F) Thin, filamentous, partially acid-fast rods with a beaded appearance within the necrotic tissue background are visible. Branching within visualized organisms was not identified. Arrows indicate N. ignorata bacteria. Fite–Faraco stain; original magnification × 100.

Main Article

Page created: December 31, 2025
Page updated: January 29, 2026
Page reviewed: January 29, 2026
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