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Volume 32, Number 10—October 2026

Dispatch

Chlamydia psittaci Meningitis, Chile, 2023

Yazmin Ivana Pinos GarciaComments to Author , Cristian Rosas, Josefa Estefania Elmohrez, Jose Vicente Gonzalez, Teresa Tapia, and Juan Carlos Hormazabal
Author affiliation: Universidad Austral de Chile, Facultad de Medicina, Osorno, Chile (Y.I. Pinos Garcia, J.E. Elmohrez); Hospital Base San Jose Osorno, Osorno (Y.I. Pinos Garcia, J.V. Gonzalez); SEREMI de Salud de Los Lagos, Osorno (C. Rosas); Institute of Public Health of Chile, Santiago, Chile (T. Tapia, J.C. Hormazabal)

Main Article

Table

Molecular and serologic diagnostic testing results for a study of Chlamydia psittaci meningitis, Chile, 2023*

Pathogen Specimen Method Target or antibody Result
Parvovirus B19 CSF qPCR NS1, VP1 Negative
Multiplex meningitis/encephalitis panel† CSF Real-time multiplex PCR assay Pathogen-specific nucleic acid targets Negative
Brucella spp. CSF qPCR bcsp31, IS711 Negative
Leptospira spp. CSF qPCR lipL32 or 16S; specify Negative
Chlamydia psittaci CSF qPCR IncA and CPSIT_0607 Positive
Toxoplasma gondii CSF qPCR B1, REP-529 Negative
Coxiella burnetii Serum Serology IFA Phase I and II for IgG, IgM Negative
Brucella spp. Serum Serology ELISA Rose Bengal, SAT, ELISA; specify Negative
Leptospira spp. Serum Serology ELISA IgM Negative
C. psittaci Serum Serology IFA IgG, IgM Positive IgM and IgG

*Testing performed on CSF and serum samples for routine and zoonotic pathogens. B1, 35-fold repetitive B1 gene of Toxoplasma gondii; bcsp31, 31 kDa Brucella immunogenic protein gene; CPSIT_0607, DNA sequence gene to C. psittaci hypothetical protein; CSF, cerebral spinal fluid; IFA, indirect immunofluorescence assay; IncA, inclusion membrane protein A; IS711, insertion sequence 711 of Brucella genus; lipL32, recombinant leptospiral outer membrane protein gene; NS1, nonstructural protein 1; qPCR, quantitative PCR; REP-529, noncoding 529-bp DNA fragment that is repeated 200–300 times; SAT, standard agglutination test; VP1, viral protein 1. †Allplex Meningitis-V1 and Meningitis-V2 Assays (Seegene Inc., https://www.seegene.com).

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Page created: September 21, 2026
Page updated: September 28, 2026
Page reviewed: September 28, 2026
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