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Volume 32, Number 3—March 2026

Research Letter

CCHFV Seroprevalence among Hunter-Gatherers, Northeastern Democratic Republic of the Congo

Dacquin M. KasumbaComments to Author , Samuel M. Shamamba, Ange Y. Mubiala, Bobo N. Bazola, Amanda C. Horton, Charles Ndawula, Jean-Jacques Muyembe-Tamfum, and Jean-Christophe Sabue Mulangu
Author affiliation: Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo (D.M. Kasumba, S.M. Shamamba, A.Y. Mubiala, B.N. Bazola, J.-J. Muyembe-Tamfum, J.-C.S. Mulangu); Université de Kinshasa Faculty of Medicine, Kinshasa (D.M. Kasumba, J.-C.S. Mulangu); United Kingdom Health Security Agency, Porton Down, UK (A.C. Horton); National Livestock Resources Research Institute, Entebbe, Uganda (C. Ndawula); Global Medical Affairs, Ridgeback Biotherapeutics, Miami, Florida, USA (J.-C.S. Mulangu)

Main Article

Table

Characteristics of subjects in a study of CCHFV seroprevalence among hunter-gatherers, northeastern Democratic Republic of the Congo *

Characteristics CCHFV serology, no. (%)
 p value OR (95% CI)
Total, n = 300 Negative, n = 288 Positive, n = 12
Sex
M 150 (50) 148 (51.4) 2 (16.7)
F
 150 (50)
 140 (48.6)
 10 (83.3)
 0.035
 5.286 (1.138–24.549)
Mean age, y +SD
 32.2 +14.6
 32.3 +14.5
 29.9 +17.5
 0.649†
 0.988 (0.948–1.031)
Professional activity
Hunting 180 (60) 178 (61.8) 2 (16.7) 0.004 8.091 (1.740–37.616)
Other/not described
 120 (40)
 110 (38.2)
 10 (83.3)
Animal contact‡
Rat 216 (72.0) 209 (72.6) 7 (58.3) 0.282 1.890 (0.583–6.128)
Bat 224 (74.7) 215 (74.7) 9 (75) 0.978 0.982 (0.259–3.724)
Monkey 273 (91.0) 261 (90.6) 12 (100) 0.610 0 (0–0.018)

*p value calculated by Fisher exact test, except as indicated. CCHFV, Crimean-Congo hemorrhagic fever virus; OR, odds ratio. †p value calculated by Student t-test. ‡>1 animal exposure type possible.

Main Article

Page created: February 09, 2026
Page updated: March 20, 2026
Page reviewed: March 20, 2026
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