Volume 32, Number 3—March 2026
Research Letter
Indeterminant Interferon-γ Release Assays in Refugee Children with Splenomegaly, Uganda, 2020–2023
Christina R. Phares
, Moses Mwesigwa, and Sean R. Toney
, Moses Mwesigwa, and Sean R. Toney
Table
Interferon-γ release assay result by splenomegaly status by age group among US-bound refugee children examined in Uganda, 2020–2023*
| Age group and splenomegaly status | Assay result, no. (%) |
Prevalence ratio (95% CI) | |
|---|---|---|---|
| Indeterminate, n = 126 | Not indeterminate, n = 1,737 | ||
| Age 2–14 y, N = 1,863 | |||
| Splenomegaly, n = 177 | 30 (16.9) | 147 (83.1) | 3.0 (2.0–4.1) |
| No splenomegaly, n = 1,686 |
96 (5.7) |
1,590 (94.3) |
NA |
| Age 2–4 y, n = 419 | |||
| Splenomegaly, n = 24 | 4 (16.7) | 20 (83.3) | 1.6 (0.6–4.0) |
| No splenomegaly, n = 395 |
42 (10.6) |
353 (89.4) |
NA |
| Age 5–14 y, n = 1,444 | |||
| Splenomegaly, n = 153 | 26 (17.0) | 127 (83.0) | 4.1 (2.6–6.3) |
| No splenomegaly, n = 1,291 | 54 (4.2) | 1,237 (95.8) | NA |
*NA, not applicable.
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Page updated: March 20, 2026
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