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Volume 32, Number 6—June 2026

Research

Identification of Novel Recombinant Human Adenovirus Genotype B117 from Pediatric Cases, China

Jinjin Wang1, Ling Jing1, Yali Duan, Xiaolei Guan, Yue Cui, Junhong Ai, Ran Wang, Xiangpeng Chen, Yuhai Bi, Xiaomei Liu, Baoping Xu2, Yun Zhu2, and Zhengde Xie2Comments to Author 
Author affiliation: Beijing Children’s Hospital, Capital Medical University, Beijing, China (J. Wang, Y. Duan, X. Guan, Y. Cui, J. Ai, R. Wang, X. Chen, X. Liu, B. Xu,Y. Zhu, Z. Xie); Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing (L. Jing); Chinese Academy of Sciences, Beijing (Y. Bi).

Main Article

Figure 1

Phylogenetic analysis of the whole genome and 3 major capsid protein genes of 2 novel strains and other species HAdV-B genotypes from a study of novel recombinant human adenovirus genotype B117 from 2 pediatric cases, China. A) The phylogenetic tree of the whole genome, constructed by the general time reversible model. B) The phylogenetic tree of the penton base gene, constructed by the Kimura 2-parameter model. C, D) Phylogenetic trees of hexon (C) and fiber (D) genes, constructed by the Hasegawa-Kishino-Yano model. All trees were constructed by the maximum-likelihood method by using 1,000 replicates. Red dots indicate the 2 novel strains obtained in this study. Scale bars indicate nucleotide substitutions per site. HAdV, human adenovirus.

Figure 1. Phylogenetic analysis of the whole genome and 3 major capsid protein genes of 2 novel strains and other species HAdV-B genotypes from a study of novel recombinant human adenovirus genotype B117 from 2 pediatric cases, China. A) The phylogenetic tree of the whole genome, constructed by the general time reversible model. B) The phylogenetic tree of the penton base gene, constructed by the Kimura 2-parameter model. C, D) Phylogenetic trees of hexon (C) and fiber (D) genes, constructed by the Hasegawa-Kishino-Yano model. All trees were constructed by the maximum-likelihood method by using 1,000 replicates. Red dots indicate the 2 novel strains obtained in this study. Scale bars indicate nucleotide substitutions per site. HAdV, human adenovirus.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: April 30, 2026
Page updated: June 01, 2026
Page reviewed: June 01, 2026
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