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Volume 32, Number 6—June 2026

Research

Identification of Novel Recombinant Human Adenovirus Genotype B117 from Pediatric Cases, China

Jinjin Wang1, Ling Jing1, Yali Duan, Xiaolei Guan, Yue Cui, Junhong Ai, Ran Wang, Xiangpeng Chen, Yuhai Bi, Xiaomei Liu, Baoping Xu2, Yun Zhu2, and Zhengde Xie2Comments to Author 
Author affiliation: Beijing Children’s Hospital, Capital Medical University, Beijing, China (J. Wang, Y. Duan, X. Guan, Y. Cui, J. Ai, R. Wang, X. Chen, X. Liu, B. Xu,Y. Zhu, Z. Xie); Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing (L. Jing); Chinese Academy of Sciences, Beijing (Y. Bi).

Main Article

Table

Nucleotide and amino acid between BJ-2024-563/2019 HAdV-B isolate and counterparts from other HAdV-B genotypes from study of novel recombinant human adenovirus genotype B117 from 2 pediatric cases, China*

Genotype Nucleotide/amino acid identity, %
Whole genome Penton base Hexon Fiber E1 E2 E3 E4
HAdV-3 96.8/95 98.5/99 97.4/97.3 64.3/57.3 96.9/94.2 98.2/96.4 94.7/92.1 98.5/97.5
HAdV-7 97.2–97.7/
95.4–95.8		 99.3–99.6/
99.4–99.6		 95.4–97.2/
96.2–97.8		 97.2–97.9/
96.6–97.8		 97.7–98.4/
95.3–96		 85.8–98.2/
83.1–96.5		 95.8–97.2/
92.4–94.1		 97.9–99.1/
95.1–97.9
HAdV-11 82.9/73.1 79.5/83.5 78.5/85.3 92.5/91.3 80.6/57.4 55.9/49.2 76.6/63.6 95.5/90.1
HAdV-14 82.6/72.4 80.4/83.6 78/84.7 91.6/89.8 79.8/55.7 73.3/61.5 76.3/62.8 95.5/89.8
HAdV-16 93.6/91.2 93.7/94.4 79.9/86.5 59/52.8 96.8/93.4 96.6/93.1 95.3/92.6 72.3/65.8
HAdV-21 92.4/88.7 83.7/85.6 80.6/85.5 65.5/58.7 93.8/89.7 65/63.3 87.7/85.2 95.2/93.1
HAdV-34 82.2/72 79.9/83.5 77.4/84.2 66.4/60.2 77.8/54.5 79.9/66.2 69.7/58.2 93/88.3
HAdV-35 82.1/72.1 79.5/83.3 78/84.7 66.2/59.9 78/55.1 55.8/49.1 45.9/37.7 83.9/80.7
HAdV-50 92.4/88.7 83.4/85.4 81.5/86 65.4/58.4 96.1/92.3 83/75.8 96/93.2 98.2/96.3
HAdV-55 82.6/72.5 80.3/83.3 78.7/85 91.2/88.8 68.9/48.3 55.6/48.8 76.2/62.6 95.3/89.8
HAdV-66 96.1/94.4 99.6/99.8 95.5/96.3 65/58.5 95.4/94.1 85.8/83.3 88.5/86.3 95.6/94.8
HAdV-68 94.9/92.2 93.7/94.2 96/97.2 59/52.5 93.8/89.8 85.6/82.7 88.1/85.3 90.4/81.9
HAdV-76 85.2/76.1 83.8/85.8 79.8/85.1 58.7/53.3 83.7/65.8 79.4/70.6 75.8/65.4 79/60.8
HAdV-77 82.7/72.9 80/83.8 77.7/84.2 94.6/92.5 77.9/54.9 74.1/62.2 69.7/57.9 93.1/88.6
HAdV-78 83.1/73.3 80/83.8 78.3/84.9 94.6/92.5 78.2/55.5 74/62.3 76.7/63.4 93.2/89.1
HAdV-79 82.9/73 80/83.8 77.4/84.1 92.4/91.3 80.6/57.7 74/62.2 69.7/57.9 93.1/88
HAdV-106 82.3/72.3 80/83.5 78.4/85 66.3/59.9 78.2/55.2 55.8/49 69.7/58.2 84.2/80.9
HAdV-114 98–98.2/
97.1–97.4		 99.6–99.8/
99.4–99.8		 98.1–98.2/
97.6–97.7		 64.8–65/
58.2–58.5		 98.1–99.7/
97.5–99.4		 88.1–99.7/
87–99.3		 96.4–96.6/
94.6–94.8		 99.3–99.5/
98.7–99

*There are high nucleotide and amino acid identities of the whole genome, penton base, hexon, fiber and E1–E4 sequences of the 2 novel strains obtained in this study, and according to nucleotide and amino acid identity analyses, the results were coincident. For this reason, BJ-2024-563/2019 was chosen as the representative to show the results. HAdV, human adenovirus.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

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Page updated: June 01, 2026
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