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Volume 32, Number 6—June 2026

Research

Characteristics of Plausible Source Cases Responsible for Recent Mycobacterium tuberculosis Transmission, United States, 2018–2022

Steve Kammerer, Daniel Flanagan, Kala Raz, Tambi Shaw, Jonathan Wortham, and Sarah TalaricoComments to Author 
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Kammerer, K. Raz, J. Wortham, S. Talarico); Emory University, Atlanta (D. Flanagan); California Department of Public Health, Richmond, California, USA (T. Shaw)

Main Article

Figure 1

Determination of the most likely plausible source cases responsible for recent Mycobacterium tuberculosis transmission, United States, 2018–2022. Flowchart shows the structured decision process used to identify the most likely plausible source case. The algorithm evaluated SNP differences, epidemiologic links in the NTSS, and an index of infectiousness. If ties remained after applying those criteria, 1 plausible source case was randomly selected from the remaining candidates. CXR, chest radiograph; CT, computed tomography; NTSS, National Tuberculosis Surveillance System; SNP, single-nucleotide polymorphism; TB, tuberculosis.

Figure 1. Determination of the most likely plausible source cases responsible for recent Mycobacterium tuberculosis transmission, United States, 2018–2022. Flowchart shows the structured decision process used to identify the most likely plausible source case. The algorithm evaluated SNP differences, epidemiologic links in the NTSS, and an index of infectiousness. If ties remained after applying those criteria, 1 plausible source case was randomly selected from the remaining candidates. CXR, chest radiograph; CT, computed tomography; NTSS, National Tuberculosis Surveillance System; SNP, single-nucleotide polymorphism; TB, tuberculosis.

Main Article

Page created: April 13, 2026
Page updated: June 01, 2026
Page reviewed: June 01, 2026
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