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Volume 32, Number 7—July 2026

Research

Prognostic Value of PCR Cycle Threshold Value in Crimean-Congo Hemorrhagic Fever, Iraq, 2022–2023

Raghad I. Khaleel, Ihab R. Aakef, Riyadh A. Al-hilfi, Hussein A. Hasan, Iman M. Aufi, Hawraa A. Shakir, Ahmed A. Hussein, Noora A. Abdulhadi, Zainb A. Mohsin, Amal A. Raheem, Sarah W. Ahmed, Ghazwan A. Baghdadi, Chiori Kodama, Antoine Chaillon, Anaïs LegandComments to Author , Pierre Formenty, Sinan G. Mahdi, and Adnan Khamasi
Author affiliation: Central Public Health Laboratory, Baghdad, Iraq (R.I. Khaleel, H.A. Hasan, I.M. Aufi, H.A. Shakir, A.A. Hussein, N.A. Abdulhadi, Z.A. Mohsin, A.A. Raheem, S.W. Ahmaed); Communicable Disease Control Center, Baghdad (I.R. Aakef, G.A. Baghdadi, S.G. Mahdi); Directorate of Public Health, Ministry of Health, Baghdad (R.A. Al-hilfi); World Health Organization Eastern Mediterranean Regional Office, Cairo, Egypt (C. Kodama); World Health Organization Emergencies Programme, Geneva, Switzerland (A. Chaillon, A. Legand, P. Formenty); World Health Organization Country Office, Baghdad (A. Khamasi)

Main Article

Figure 4

Distribution of confirmed Crimean-Congo hemorrhagic fever patients (n = 915) by Ct value category and corresponding CFR in study of prognostic value of PCR cycle threshold for Crimean-Congo hemorrhagic fever, Iraq, 2022–2023. Case fatality ratio is plotted for each Ct values category, indicating an inverse correlation between Ct value and outcome. Red dashed line shows the smoothed CFR trend across categories (p = 3.28 × 10−5; locally estimated scatterplot smoothing fit, p<0.05). CFR, case-fatality ratio; Ct, cycle threshold.

Figure 4. Distribution of confirmed Crimean-Congo hemorrhagic fever patients (n = 915) by Ct value category and corresponding CFR in study of prognostic value of PCR cycle threshold for Crimean-Congo hemorrhagic fever, Iraq, 2022–2023. Case fatality ratio is plotted for each Ct values category, indicating an inverse correlation between Ct value and outcome. Red dashed line shows the smoothed CFR trend across categories (p = 3.28 × 10−5; locally estimated scatterplot smoothing fit, p<0.05). CFR, case-fatality ratio; Ct, cycle threshold.

Main Article

Page created: May 21, 2026
Page updated: June 26, 2026
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