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Investigation of Donor-Transmitted Strongyloides stercoralis Infections in Solid Organ Transplant Recipients, United States, 2012–2024
Kerry R. Gainor, Dawn Blackburn, Pallavi Annambhotla, Sridhar V. Basavaraju, Katherine E. Bowden, Diana Martin, David A. Baran, Irene Frantzis, Irene D. Lytrivi, Julia Simkowski, Danielle Stanek, Susan P. Montgomery, and Rebecca J. Chancey
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (K.R. Gainor, D. Blackburn, P. Annambhotla, S.V. Basavaraiu, K.E. Bowden, D. Martin, S.P. Montgomery, R.J. Chancey); Cleveland Clinic Florida, Weston, Florida, USA (D.A. Baran); Columbia University Irving Medical Center, New York, New York, USA (I. Frantzis, I.D. Lytrivi); Cleveland Clinic, Cleveland, Ohio, USA (J. Simkowski); Florida Department of Health, Tallahassee, Florida, USA (D. Stanek).
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Figure
Figure. Case determination algorithm used for analysis in the Centers for Disease Control and Prevention investigations of potential donor-derived strongyloidiasis, United States, 2012–2024. Each investigation begins with a trigger, either recipient positive posttransplant (1) or donor positive (2), and follows the algorithm to a designated case determination based on clinical, laboratory, and epidemiologic data and our case definitions. Determination categories include proven, excluded, NINDT, IWDT, probable, possible, and inconclusive cases. IWDT, intervention without disease transmission; NINDT, no intervention and no disease transmission.
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