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Volume 32, Number 9—September 2026

Research Letter

Emergence of Oropouche Virus, Venezuela, 2025

Pierina D’Angelo1, Lieska Rodríguez1, Víctor Alarcón, Yoneira Sulbarán, Norca García, Giulianna Antonelli, Marwan Aguilar, Martha Bravo, Zoila C. Moros, Carmen L. Loureiro, Ferdinando Liprandi, José L. Zambrano, Rossana C. Jaspe, and Flor H. PujolComments to Author 
Author affiliation: Instituto Nacional de Higiene “Rafael Rangel,” Caracas, Venezuela (P. D’Angelo, L. Rodríguez, V. Alarcón, N. García, G. Antonelli, M. Aguilar, M. Bravo); Instituto Venezolano de Investigaciones Científicas, Caracas (Y. Sulbarán, Z.C. Moros, C.L. Loureiro, F. Liprandi, J.L. Zambrano, R.C. Jaspe, F.H. Pujol)

Main Article

Figure 2

Phylogenetic analysis of OROV cases in Venezuela, 2025. Maximum-likelihood phylogenetic analysis for each genomic segment of the OROV genome: A) large genome segment sequences; B) medium genome segment sequences; C) small genome segment sequences. The isolates are named according to their accession number in GenBank or GISAID (https://www.gisaid.org), including the country and year of collection of each sample. Blue indicates the OROVBR2015–2024 clade and purple the OROVPe/Co/Ec2008–2021 clade. Bold indicates the sequences of the Venezuela isolates. The tree scale indicates the average number of nucleotide substitutions per site. Blue circles indicate bootstrap values >80. OROV, Oropouche virus.

Figure 2. Phylogenetic analysis of OROV cases in Venezuela, 2025. Maximum-likelihood phylogenetic analysis for each genomic segment of the OROV genome: A) large genome segment sequences; B) medium genome segment sequences; C) small genome segment sequences. The isolates are named according to their accession number in GenBank or GISAID (https://www.gisaid.org), including the country and year of collection of each sample. Blue indicates the OROVBR2015–2024 clade and purple the OROVPe/Co/Ec2008–2021 clade. Bold indicates the sequences of the Venezuela isolates. The tree scale indicates the average number of nucleotide substitutions per site. Blue circles indicate bootstrap values >80. OROV, Oropouche virus.

Main Article

1These first authors contributed equally to this article.

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