Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 4, Number 3—September 1998
THEME ISSUE
ICEID 1998
New Agents and Disease Associations

The Emergence of Bovine Spongiform Encephalopathy and Related Diseases

Sir John Pattison
Author affiliation: Medical School of University College London, London, United Kingdom

Main Article

Table 2

Predictions of new infections and cases of BSEa from 1996-2001b

New Infections
 Cases
Year Expected value 95% Prediction interval Expected value 95% Prediction interval
1996 189 (155-11,300) 7,386 (6,541-8,856)
1997 95 (63-236) 4,111 (3,006-7,664)
1998 38 (21-214) 1,864 (1,153-7,052)
1999 12 (5-162) 682 (388-5,909)
2000 3 (1-86) 221 (128-3,660)
2001 1 (0-33) 72 (45-1,592)

aBovine spongiform encephalopathy.
bInformation extracted from (7).

Main Article

References
  1. Wells  GAH, Scott  AC, Johnson  CI, Gunning  RF, Hancock  RD, Jeffrey  M, A novel progressive spongiform encephalopathy in cattle. Vet Rec. 1987;121:419–20.PubMedGoogle Scholar
  2. Wilesmith  JW, Hoinville  LJ, Ryan  JBM, Sayers  AR. Bovine spongiform encephalopathy: aspects of the clinical picture and analyses of possible changes. Vet Rec. 1992;130:197–201.PubMedGoogle Scholar
  3. Fraser  H, McConnell  I, Wells  GAH, Dawson  M. Transmission of bovine spongiform encephalopathy to mice. Vet Rec. 1988;123:472.PubMedGoogle Scholar
  4. Dawson  M, Wells  GAH, Parker  BNJ. Preliminary evi-dence of the experimental transmissibility of bovine spon-giform encephalopathy to cattle. Vet Rec. 1990;126:112–3.PubMedGoogle Scholar
  5. Wilesmith  JW, Wells  GAH, Cranwell  MP, Ryan  JBM. Bovine spongiform encephalopathy: epidemiological studies. Vet Rec. 1988;123:638–44.PubMedGoogle Scholar
  6. Stekel  DJ, Nowak  MA, Southwood  TRE. Prediction of future BSE spread. Nature. 1996;381:119. DOIPubMedGoogle Scholar
  7. Anderson  RM, Donnelly  CA, Ferguson  NM, Woolhouse  MEJ, Watt  CJ, Udy  HJ, Transmission dynamics and epidemiology of BSE in British cattle. Nature. 1996;382:779–88. DOIPubMedGoogle Scholar
  8. Donnelly  CA, Ghani  AC, Ferguson  NM, Wilesmith  JW, Anderson  RM. Analysis of the bovine spongiform encephalopathy study: evidence for direct maternal transmission. Appl Stat. 1997;43:321–44. DOIGoogle Scholar
  9. Lawson  C, Herd  L, eds. BSE Enforcement Bulletin 1998. Ministry of Agriculture, Fisheries and Food; Bull. No. 20; p. 2.
  10. Will  RG, Ironside  JW, Zeidler  SN, Cousens  SN, Estibeiro  K, Alperovitch  A, A new variant of Creutzfeldt-Jakob disease in the UK. Lancet. 1996;347:921–5. DOIPubMedGoogle Scholar
  11. Zeidler  M, Stewart  GE, Barraclough  CR, Bateman  DE, Bates  D, Burn  DJ, New variant Creutzfeldt-Jakob disease: neurological features and diagnostic tests. Lancet. 1997;350:903–7. DOIPubMedGoogle Scholar
  12. Hill  AF, Zeidler  M, Ironside  J, Collinge  J. Diagnosis of new variant Creutzfeldt-Jakob diseases by tonsil biopsy. Lancet. 1997;349:99–100. DOIPubMedGoogle Scholar
  13. Collinge  J, Sidle  KCL, Meads  J, Ironside  J, Hill  AF. Molecular analysis of prion strain variation and the aetiology of `new variant' CJD. Nature. 1996;383:685–90. DOIPubMedGoogle Scholar
  14. Bruce  ME, Will  RG, Ironside  JW, McConnell  I, Drummond  D, Suttie  A, Transmissions to mice indicate that `new variant' CJD is caused by the BSE agent. Nature. 1997;389:498–501. DOIPubMedGoogle Scholar
  15. Cousens  SN, Vynnycky  E, Zeidler  M, Will  RG, Smith  PG. Predicting the CJD epidemic in humans. Nature. 1997;385:197–8. DOIPubMedGoogle Scholar

Main Article

Page created: December 14, 2010
Page updated: December 14, 2010
Page reviewed: December 14, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external