Volume 7, Number 1—February 2001
Research
Preoperative Drug Dispensing as Predictor of Surgical Site Infection1
Keith S. Kaye*
, Kenneth Sands*, James G. Donahue†, K. Arnold Chan†, Paul Fishman‡, and Richard Platt†
, Kenneth Sands*, James G. Donahue†, K. Arnold Chan†, Paul Fishman‡, and Richard Platt†
Table 1
Characteristics of the study population
| Controls | Odds ratioa | |||
|---|---|---|---|---|
| Variable | Cases (no.=191) | (no.=372) | p value | (95% CI) |
| Mean age (yrs) | 51.2 | 51.5 | NA | NA |
| Male sex (%) | 91 (47.6) | 182 (48.9) | NA | NA |
| NNISb wound class, | 8 (4.2) | 13 (3.5) | NA | NA |
| contaminated or infected (%) | ||||
| Surgical Specialty(%) General Cardiac Orthopedic Plastic Urologic Vascular Gynecologic Neurosurgical Other | 54 (28.3) 41 (21.5) 31 (16.2) 17 (8.9) 14 (7.3) 10 (5.2) 5 (2.6) 4 (2.1) 15 (7.9) | 107 (28.8) 78 (21.0) 63 (16.9) 30 (8.1) 27 (7.3) 19 (5.1) 10 (2.7) 8 (2.2) 30 (7.8) | NA | NA |
| General anesthesia (%) | 132 (69.1) | 222 (59.7) | 0.004 | 2.19 (1.29,3.72) |
| Median duration of surgery (min) (IQRc) | 105 (55-211) | 83 (40-154) | <0.001d | 1.75 (1.34,2,29)d |
| Emergent procedure (%) | 11 (5.8) | 10 (2.7) | 0.07 | 2.21 (0.94,5.21) |
| ASA score (%) Missing 1 2 3 4 5 | 30 (15.7) 32 (16.8) 62 (32.5) 59 (30.9) 8 (4.2) 0 | 80 (21.5) 83 (22.3) 130 (34.9) 74 (19.9) 5 (1.4) 0 | 0.002f | 2.0 (1.4, 2.9)f |
| Chronic disease score Median (IQR) | 2,219 (1,101-5,673) | 1,641 (809-3,588) | 0.09 | NA |
aOR=odds ratio.
bNNIS=National Nosocomial Infection Surveillance System.
cIQR=Interquartile range.
dValues are for duration as a 6-level ordinal variable. Risk is per-unit increase in duration category.
eASA=American Society of Anesthesiologists phycial status scale.
fASA as a four-level ordinal variable, excluding missing values. Risk is per-unit increase in ASA category, missing values excluded.
1This study was presented in part at the Society for Healthcare Epidemiology of America annual meeting, San Francisco, California, April 1999, and at the 4th Decennial International Conference on Nosocomial and Health Care-Associated Infections, Atlanta, Georgia, March 2000.
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