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Volume 7, Number 1—February 2001


Preoperative Drug Dispensing as Predictor of Surgical Site Infection1

Keith S. Kaye*Comments to Author , Kenneth Sands*, James G. Donahue†, K. Arnold Chan†, Paul Fishman‡, and Richard Platt†
Author affiliations: *Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA; †Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; ‡Group Health Cooperative of Puget Sound, Seattle, Washington, USA; *†the Eastern Massachusetts CDC Prevention Epicenter

Main Article

Table 2

Relationships between chronic disease score, American Society of Anesthesiologists (ASA) score, and surgical site infection

Unadjusteda Adjustedb
Cases Controls
Variable (n=191) (n=372) p value ORc (95% CI) p value OR (95% CI)
Chronic disease score >5,000 (%) 55 (28.8) 60 (16.1) < 0.001 2.6 (1.6-4.2) 0.001 2.6 (1.5-4.7)
ASA >3 (%) 67(35.1)d 79 (21.2)e < 0.001 3.1 (1.7-5.5) 0.03 2.0 (1.1-3.7)

aUnadjusted values are controlled for age, sex, and procedure duration because of the matching process used to select uninfected subjects.
bAdjusted for chronic disease score 5,000, ASA 3, type of anesthesia, emergent nature of the procedure, procedure duration (ordinal), and wound class.
cOR=Odds ratio.
dThirty (15.7%) cases had missing ASA scores.
eEighty-two (21.7%) controls had missing ASA scores.

Main Article

1This study was presented in part at the Society for Healthcare Epidemiology of America annual meeting, San Francisco, California, April 1999, and at the 4th Decennial International Conference on Nosocomial and Health Care-Associated Infections, Atlanta, Georgia, March 2000.