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Volume 7, Number 1—February 2001


Active Bacterial Core Surveillance of the Emerging Infections Program Network

Anne Schuchat*Comments to Author , Tami Hilger*, Elizabeth Zell*, Monica M. Farley†, Arthur L. Reingold‡, Lee H. Harrison§, Lewis Lefkowitz¶, Richard N. Danila**, Karen Stefonek††, Nancy Barrett‡‡, Dale Morse§§, Robert W. Pinner*, and for the Active Bacterial Core Surveillance Team of the Emerging Infections Program Network
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Georgia Emerging Infection Program (Georgia Department of Human Resources, Division of Public Health, Emory University School of Medicine, and the Atlanta Veterans Administration Medical Center) Atlanta, Georgia, USA; ‡California Department of Health Services and UC Berkeley School of Public Health, Berkeley, California, USA; §Maryland Department of Health and Mental Hygiene and Johns Hopkins University School of Public Health, Baltimore, Maryland, USA; ¶Tennessee Department of Health and Vanderbilt University Medical Center, Nashville, Tennessee, USA; **Minnesota Department of Health, St. Paul, Minnesota, USA; ††Oregon Department of Human Resources, Portland, Oregon, USA; ‡‡Connecticut Department of Public Health, Hartford, Connecticut, USA; §§New York State Department of Health, Albany, New York, USA

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Table 2

Incidence, case-fatality ratio, projected U.S. cases and deaths, and proportion nonsusceptible to penicillin of invasive disease identified in the Active Bacterial Core surveillance (ABCs), 1998

Group A Group B Haemophilus Neisseria Streptococcus
Streptococcus Streptococcus influenzae meningitidis pneumoniae
Aggregate incidencea 3.8 6.5 1.4 1.0 24.1
Range by areaa 2.6 - 4.1 4.8 - 8.5 1.1 - 2.3 0.6 - 2.0 20.0-28.9
Case- fatality ratio in 12.2% 9.5% 13.9% 13.7% 9.3%
ABCs areas
Projected U.S. cases 10,200 17,400 3,900 2,500 63,000
Projected U.S. deaths 1,300 1,700 500 400 6,100
Penicillin nonsuscep-tibilityb 0 0 - - 1.1% 25.0%

aIncidence = cases per 100,000.
bNonsusceptible includes isolates classified as either intermediate or resistant to penicillin. Results reflect testing of group A streptococcal isolates from 1997 (n=183) and group B streptococcal isolates from 1997 and 1998 combined (n=188).

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